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Research1 published in the American Heart Association journal Circulation: Arrhythmia and Electrophysiology found an association between drinking sweetened beverages and atrial fibrillation. Atrial fibrillation, also called AFib, is an abnormal and often rapid heartbeat that occurs when the upper chambers in the heart (atria) beat out of sync with the lower chambers (ventricles).2

It’s a common symptom in people with heart failure or heart disease and one of the most common arrhythmias (irregular heartbeats) that affects more than 2 million U.S. adults. AFib can sometimes go away on its own, but it also can become more frequent with longer-lasting episodes that can lead to serious complications like stroke and heart failure.

The symptoms of AFib can look like other health problems, which is why it is crucial to understand the condition and receive the correct diagnosis. For example, the declining ability to pump blood to the lungs and elsewhere in the body can lead to lightheadedness, dizziness and fatigue, which are symptoms that can be attributed to several other health conditions.

AFib may make you feel like your heart has skipped a beat or is fluttering or pounding. Your risk increases with age, but lifestyle and dietary factors can also increase your risk, which is exactly what researchers found when they sought to determine if there was an association between drinking sweetened beverages and AFib.

Diet and Regular Soda Raises Heart Risk

The researchers acknowledged3 that a past association between sweetened beverages and cardiometabolic disease has been reported, but an association with atrial fibrillation was unclear. The study enrolled 201,856 participants who did not have AFib at the time the study began, had completed a 24-hour diet questionnaire and had genetic data available.

Research has found a genetic component to AFib. Genome-wide studies identified 140 genetic loci that are linked to the development of AFib.4 However, while genetic implications put an individual at higher risk of developing the condition, it is not a guarantee that the condition will develop.

There was a median follow-up of 9.9 years, during which 9,362 incidents of AFib were documented.5 The researchers evaluated the consumption of sugar-sweetened beverages (SSB), artificially sweetened beverages (ASB) and pure fruit juice. The data showed that people who drank greater than 2 liters per week of sugar-sweetened or artificially sweetened beverages increased their risk of AFib, with those who drank artificially sweetened beverages experiencing a higher risk.

The highest risk was observed in people who had a genetic risk and consumed more than 2 liters of artificially sweetened beverages, while the lowest risk was observed in those who had a low genetic risk and consumed less than 1 liter of pure juice per week.

The association between sweetened beverages and AFib persisted even after adjustments were made for genetic susceptibility to the heart condition. “This study does not demonstrate that consumption of SSB and ASB alters AF risk but rather that the consumption of SSB and ASB may predict AF risk beyond traditional risk factors,” the researchers concluded.6

Many people reach for an artificially sweetened beverage advertising zero calories and sugar because they know other sodas and juices contain an alarming amount of both. Drinking a beverage advertised with zero calories and sugar can feel like you’re making better choices but as these researchers have demonstrated, artificial sweeteners may cause more harm than good.

While the data from the current study demonstrates a higher risk of consuming ASB, a press release from the American Heart Association about the study also noted that people who drink 2 liters of SSB each week increase their risk of AFib by 10%.7 Kris-Etherton, an emeritus professor of nutritional sciences at Penn State University, commented on the results of the study from China, saying:

“This is the first study to report an association between no- and low-calorie sweeteners and also sugar-sweetened beverages and increased risk of atrial fibrillation.

While there is robust evidence about the adverse effects of sugar-sweetened beverages and cardiovascular disease risk, there is less evidence about adverse health consequences of artificial sweeteners. In the meantime, water is the best choice, and, based on this study, no- and low-calorie sweetened beverages should be limited or avoided.”

Sweeteners in Diet Soda Can Destroy Your Gut Microbiome

While refined sugar feeds harmful, disease-causing bacteria in the gut,8 artificial sweeteners cause DNA damage in, and interfere with, the normal activity in gut bacteria. The artificial sweeteners reviewed in one study9 included aspartame, sucralose, saccharin, neotame, advantame and acesulfame potassium-k.

The animal study was published in the journal Molecules, and as noted by Business Insider,10 all the sweeteners “had a toxic, stressing effect, making it difficult for gut microbes to grow and reproduce.” According to the researchers, this effect can in turn affect your body’s ability to process carbohydrates.

While, overall, all six artificial sweeteners were found to have toxic effects on gut bacteria, there were individual differences in the type and amount of damage they produced.

Saccharin caused the greatest, most widespread damage, exhibiting both cytotoxic and genotoxic effects, meaning it is toxic to cells and damages genetic information in the cell (which can cause mutations).
Neotame was found to cause metabolic disruption in mice, and raised concentrations of several fatty acids, lipids and cholesterol. Several gut genes were also decreased by this sweetener.
Aspartame and acesulfame potassium-k — The latter of which is commonly found in sports supplements — were both found to cause DNA damage.

In a carefully crafted message, Ariel Kushmaro, Ph.D., professor of microbial biotechnology at Ben-Gurion University and lead author, told Business Insider, “We are not claiming that it’s toxic to human beings. We’re claiming that it might be toxic to the gut bacteria, and by that, will influence us.”11

These data support previous research published in 2013,12 which concluded that sucralose reduces the number, and alters the composition of, gut bacteria. Animal research13 in 2008 showed sucralose could kill gut bacteria and appeared to target beneficial microorganisms to a greater extent than pathologic bacteria.

This is crucial since anytime you destroy healthy intestinal bacteria, it opens the door to increased growth of unfriendly microorganisms that can cause health problems. A 2021 study14 found three of the six commonly used artificial sweeteners impair your gut bacteria’s ability to communicate and the “effect of these artificial sweeteners on numerous molecular events that are at the core of intestinal microbial function, and by extension on the host metabolism.”

Artificial Sweetener Tricks Your Body into Storing Fat

Since the 1960s, researchers have known that your body metabolizes different types of carbohydrates in different ways, which causes hormonal and physiological responses that influence fat accumulation and metabolism.15

While the sugar industry wants you to believe that all calories are the same, you can’t undo the effects of soda by cutting back on calories in your diet since refined sugar itself wreaks havoc on your gut microbiome and your metabolism.

In late 2021,16 research showed women who consumed foods with artificial sweeteners felt hungrier and ate more food than those who simply drank a sugar-sweetened beverage. Contrary to industry claims, research shows that artificial sweeteners stimulate your appetite, increase cravings for carbohydrates and produce a variety of metabolic dysfunctions that promote fat storage and weight gain.

For a list of research supporting dysfunction in fat storage and weight gain associated with consuming artificial sweeteners see “Reconfirmed: Artificial Sweeteners Make You Sick.” There is also a mounting number of studies that have shown artificial sweeteners raise your risk of obesity and Type 2 diabetes, perhaps to an even greater degree than sugar.

One animal study17 presented at the annual Experimental Biology conference in San Diego confirmed these results while exploring how different sweeteners affect the way food is used and stored, including the effect on vascular function. The researchers concluded:18

“Overall, results of this study suggest that exposure to high glucose and artificial sweetener administration lead to unique mechanisms of vascular impairment and homeostatic alterations that may be important during the onset and progression of diabetes and obesity.”

Diet Soda Linked to Depression, Gout and More

A damaged gut microbiome, fat storage and an increased risk of obesity may help explain how diet soda is linked to so many health conditions. A 2024 study19 showed sugar-sweetened beverages (SSB) and artificially sweetened beverages (ASB) increase your risk of cardiovascular disease as an adult regardless of your activity level.

The study evaluated 13,269 cardiovascular disease events and compared the results to those who never or rarely consume sweetened beverages against those who consumed two or more each day. They found a dose-dependent response, concluding:20

“Higher SSB intake was associated with CVD risk regardless of physical activity levels. These results support current recommendations to limit the intake of SSBs even for physically active individuals.”

Data have also linked sugar and artificially sweetened beverages with an increased risk of depression. Research21 showed that drinking four servings of soda a day increased the risk of depression by 30% compared to those who did not drink sweetened beverages of any kind.

People who drank primarily diet soda had a 31% increased risk of suffering depression, regular soda was associated with a 22% increased risk and those who drank diet fruit drinks had a 51% higher risk of depression. Regular fruit drinks were associated with a more modest 8% increased risk.

For a discussion of the potential pathways sugar impacts mental health, see “How Dietary Intervention Lifts Depression.” Soda and other SSBs are a leading source of added sugar, with 6 in 10 youths and 5 in 10 adults drinking at least one beverage on any given day.22 Even the U.S. Centers for Disease Control and Prevention states:23

“Frequently drinking sugar-sweetened beverages is associated with weight gain/obesity, Type 2 diabetes, heart disease, kidney diseases, nonalcoholic liver disease, tooth decay and cavities and gout, a type of arthritis.”

However, the CDC only suggests that “limiting the amount of SSB intake can help individuals maintain a healthy weight and have a healthy diet,” stopping far short of advising Americans to ditch these unhealthy drinks to avoid chronic disease.

Aspartame Has Been Linked to Many Health Problems

Aspartame is another powerful artificial sweetener that has been linked to a significant number of health conditions. A 2022 animal study24 found that at doses equivalent to 15% below the FDA-recommended maximum daily intake for humans, aspartame produced anxiety-type behavior and changes in genetic expression in areas of the brain that regulate anxiety and fear.

These changes in the amygdala occurred in the aspartame-exposed animals and in up to two generations that descended from aspartame-exposed males. The artificial sweetener is found in a long list of processed foods and beverages. In 2023, the World Health Organization’s International Research Agency on Cancer announced that aspartame is a possible carcinogen.25

Try Swapping Your Soda for Clean Water or Hibiscus Tea

If you’re drinking artificially sweetened, zero-calorie beverages it’s important to understand that they do not help if you’re overweight or have insulin resistance. Instead, they probably will make matters worse. I firmly believe ditching soda and other sweetened beverages is one of the most important steps you can take to improve your weight and your overall health.

Remember, pure water is zero calories, and you can easily add flavor by squeezing in fresh lemon or lime or a piece of frozen fruit. If you’re looking for something that’s more than water, consider swapping it for tea instead.

Drinking tea is flavorful and adds a healthy boost to your diet. Hibiscus tea has a pleasantly sharp flavor that’s like the tartness of cranberries and you can find it in liquid extract form, which allows you to add it to your glass of water. Hibiscus tea is rich in polyphenols and has other health benefits including protecting your liver and preventing metabolic syndrome.26

Editor’s Note: This article is a reprint. It was originally published November 25, 2017.

I am so pleased to post this video and I hope it gives you as much joy as it did me when I first viewed it on 60 Minutes. It is beyond extraordinary to have a glimpse into someone as exceptionally talented as 12-year-old Alma. My only regret is that there is no way to post this without exposing you to a minutelong drug commercial, which I’m sure you realize I don’t endorse. For some of you, it may be the only time you see these commercials so let them entertain you.

Most of us are gifted with some degree of natural talent — something we do better, or with greater ease, than the average person. And then, there’s the true prodigies; people with seemingly unnatural talent. Their gift is so profound, and comes from God-only-knows-where. Alma Deutscher, from Basingstoke, England, is a perfect example of the latter.1

There are a number of musical prodigies out there, but Alma has most of them beat. She was able to name notes on the piano at age 2 and began playing piano and violin at the tender age of 3. Within a year of tutoring, she was playing Handel sonatas on the violin.

She’s now considered a virtuoso of both instruments. By the age of 4, she’d already begun composing her own melodies, and by 6 she’d written her first piano sonata. This was followed by a violin and orchestra concerto at 9.

In December last year, her full-length opera, “Cinderella,” premiered at the Casino Baumgarten Theatre in Vienna,2 the city of music, performed by the Viennese opera group, Oh!pera — an unattainable dream even for many adult composers who’ve spent a lifetime perfecting their craft. Alma, who wrote the score for every single instrument, and the lyrics, was 11 years old. The 2.5-hour long opera, with a musical score running 237 pages, received standing ovations.

Cinderella Reinvented by 11-Year-Old Prodigy

Many were also wowed by her creative reinvention of the classical tale of Cinderella. Rather than being matched with her true love by the way of a lost glass slipper of a particularly minute size — an idea Alma found to be “quite silly” — Cinderella is a talented composer and the pining prince is a poet. The tale is set in an opera production company run by the evil stepmother. The two stepsisters are divas with little talent and much vile.

Cinderella, with a natural talent for composing, is not allowed to perform. Meanwhile, the prince writes a love poem that ends up in Cinderella’s hands. Not knowing the identity of the poet, she falls in love with the words and sets them to music. After having her composition stolen by her evil stepsisters, who do their best to sing it at the ball, Cinderella finally gets her chance to perform for the prince.

The prince is enthralled by the enchanting melody, and sets out to discover who wrote the music to his poem. As in the classical story, he travels the land searching for his soulmate, but instead of looking for the foot that fits into the slipper, he sings a portion of the melody, knowing only the true composer can properly finish the song.

So, the prince falls in love with Cinderella not because of her physical beauty or tiny feet, but because of her talent, and because “he understands her,” to use Alma’s explanation. In other words, he recognizes his soulmate as a talented equal.

“I didn’t want Cinderella just to be pretty. I wanted her to have her own mind and her own spirit. And to be a little bit like me. So, I decided that she would be a composer,” Alma explains.3 “Cinderella” made its American sold-out debut December 16 at the Opera San Jose.4

Where Does the Music Come From?

Most interviews with Alma include the same question: Where does her music come from? In a “60 Minutes” interview, Scott Pelley received the following answer:5

“I don’t really know, but it’s really very normal to me to … walk around and having melodies popping into my head. It’s the most normal thing in the world. For me, it’s strange to walk around and not to have melodies popping into my head. So, if I was interviewing you, I would say, ‘Well, tell me Scott, how does it feel not having melodies popping into your head?'”

Oftentimes, the music comes when she’s most relaxed, either playing outdoors with her younger sister, or skipping rope. Her father, Guy Deutscher, a linguistics professor and amateur musician, taught her to read musical notes, but questions the influence of his role in her immense ability to create music, including scores for instruments she does not play.

He tells Pelley, “I thought it was me [that taught her to read music]. I hardly had to say [any]thing — and, you know, her piano teacher once said ‘it’s a bit difficult with Alma; it’s difficult to teach her because one always has the sense she’d ‘been there’ before.'” Alma also says she has “lots of composers” inside her mind, in a special “country” she created in her imagination.

These imaginary friends provide her with the emotional juices her tender youth lacks. Each one has their own emotional style of composing. One of them, Antonin Yellowsink, helped her compose a “dark and dramatic” violin concerto. “[S]ometimes when I’m stuck with something, when I’m composing, I go to them and ask them for advice. And quite often, they come up with very interesting things,” she says.

Would Rather Be Original Alma Than Second Mozart

Many compare Alma to Wolfgang Amadeus Mozart (1756-1791),6 one of the few childhood prodigies that can even compare to Alma’s talent. However, while flattered, Alma insists she would rather “prefer to be the first Alma than the second Mozart.” That said, she has a great affinity for the famed composer and musician, and “would have loved” to have him as a teacher.

The question is whether Alma wouldn’t have ended up teaching Mozart a thing or two. In a concerto in Israel, Alma performed one of Mozart’s piano concertos with a cadenza — a musical interlude where the orchestra goes silent, allowing the soloist to perform his or her own music. But in this case, Alma didn’t just perform Mozart’s solo. She created her own.

“It’s something that I composed because, you see, it’s a very early concerto of Mozart and the cadenza was very simple. It didn’t go to any different keys,” she tells Pelley. “And I composed quite a long one going to lots and lots of different keys doing lots of things in Mozart’s motifs,” Alma says. “So, you improved the cadenza of Mozart?” Pelley asks, to which she replies, “Well, yes.”

Robert Gjerdingen, a professor of music at Northwestern in Chicago who has acted as a “consultant to Alma’s education,” had the following to say about his star protégé:

“It’s kind of a comet that goes by and everybody looks up and just goes, ‘Wow.’ I sent her some assignments when she was six, seven, where I expected her to crash and burn, because they were very difficult.

It came back, it was like listening to a mid-18th century composer. She was a native speaker … It’s her first language — she speaks the Mozart-style. She speaks the style of Mendelssohn … She’s batting in the big leagues. And if you win the pennant, there’s immortality.”

The Many Benefits of Music

As for why she composes, Alma says her inspiration is to “make the world a better place,” and she believes beautiful music can do that. She is undoubtedly correct. Music is a form of emotional communication, an emotional protolanguage of sorts, and like emotions it can have a tremendous influence on psychological and even physical health. For example, music has been found to:

Help you exercise harder, while making it feel easier

Help Alzheimer’s patients reconnect with people around them, remember past life events and reduce agitation associated with dementia

Allow patients with Parkinson’s disease move more freely.7 The music appears to provide an external rhythm that bypasses the malfunctioning signals in the brain

Improve your mood; calm nerves; reduce stress and/or invigorate and energize

Facilitate connection and unification between people. Despite individual differences in musical preferences, classical music has been shown to elicit a very consistent pattern of brain activity in virtually all listeners. Areas activated include those involved in movement, planning, memory and attention. This brain activation creates a sort of unifying force that synchronizes and unifies people together8

What Happens in Your Brain When You Hear Music?

When you listen to music, much more is happening in your body than simple auditory processing. Research shows that music triggers activity in the nucleus accumbens, a part of your brain that releases the feel-good chemical dopamine and is involved in forming expectations. At the same time, the amygdala, which is involved in processing emotion, and the prefrontal cortex, which makes possible abstract decision-making, are also activated.9

Based on the brain activity in certain regions, especially the nucleus accumbens, captured by an fMRI imager while participants listened to music, the researchers could predict how much money the listeners were willing to spend on previously unheard music. As you might suspect, songs that triggered activity in the emotional and intellectual areas of the brain demanded a higher price.

Interestingly, the study’s lead author noted that your brain learns how to predict how different pieces of music will unfold using pattern recognition and prediction, skills that may have been key to our evolutionary progress. As reported by Time:10

“These predictions are culture-dependent and based on experience: someone raised on rock or Western classical music won’t be able to predict the course of an Indian raga, for example, and vice versa. But if a piece develops in a way that’s both slightly novel and still in line with our brain’s prediction, we tend to like it a lot. And that, says [lead researcher] Salimpoor, ‘is because we’ve made a kind of intellectual conquest.’

Music may, in other words, tap into a brain mechanism that was key to our evolutionary progress. The ability to recognize patterns and generalize from experience, to predict what’s likely to happen in the future — in short, the ability to imagine — is something humans do far better than any other animals. It’s what allowed us (aided by the far less glamorous opposable thumb) to take over the world.”

Alma’s future passion project is to write a book, turn it into a film and write the musical score. I hope you’ll take the time to view the featured 25-minute documentary about Alma Deutscher, and revel in her musical talent. You will not regret it. Then, if you’re eager for more, you can listen to some of the “Cinderella” performances in the 1.5-hour-long recording above. May she inspire you to help make the world a better place, every day.