Category: New Believers

Seed Oils Linked to Early 20th Century Heart Disease Surge

Heart disease feels like a permanent feature of modern life, but it wasn’t always that way. In the late 1800s, coronary heart disease was uncommon, and most people died from infections rather than chronic vascular problems. Today, coronary heart disease sits at the center of cardiovascular mortality, bringing with it chest pain, breathlessness, fatigue, and sudden heart attacks that often appear after years of silent damage.

That contrast alone raises a basic question you deserve an honest answer to: what fundamentally changed? The usual explanations focus on longer lifespans, better diagnostics, or individual behavior. I don’t find those answers sufficient.

When I examined long-term mortality data, one pattern stood out: something changed the internal environment of human arteries long before heart attacks became common. One change stands out because it happened quickly, affected nearly everyone, and reshaped what people ate every single day.

My paper, “Seed Oils as a Hypothesized Contributor to Heart Disease: A Narrative Synthesis,” published in the journal Cureus on January 21, 2026, explains why the widespread adoption of industrial seed oils deserves closer scrutiny.1

It synthesizes over 200 references showing that the rapid adoption of LA-rich industrial seed oils in the early 1900s preceded the surge in coronary heart disease deaths by 10 to 20 years — the exact timeframe needed for atherosclerotic plaques to develop — and that LA oxidation generates the same inflammatory aldehydes like 4-HNE now being implicated in obesity.

Coronary heart disease doesn’t begin with a heart attack. It begins quietly, with changes inside blood vessels that build year after year. To understand why heart disease became so widespread — and how you can change your own trajectory — you need to see how one dietary shift altered the internal environment of your arteries over time. I break down that evidence step by step in my paper, which you can read in full below.

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Acupuncture in the ICU — A Natural Approach to Faster Recovery

Every year, more than 5 million Americans are admitted to intensive care units (ICUs) to get life-saving treatment. Thanks to modern technology, survival rates have never been higher — however, recovery is often brutal. Up to 80% of ventilated patients experience delirium,1 and nearly half develop severe muscle weakness that can linger for months. These complications stretch hospital stays and drive costs, with ICU care expenditures averaging over $4,000 per day.2

Heavy reliance on sedatives and opioids adds another layer of risk. Ironically, the very drugs meant to ease suffering can slow recovery, extend time on mechanical ventilation, and leave patients mentally foggy for weeks after discharge.3 In response to these concerns, researchers are exploring gentler, complementary approaches to support healing — including acupuncture, a therapy rooted in ancient tradition.

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A Legacy of Helping People Feel Less Pain

Acupuncture has been practiced for over 2,500 years in Traditional Chinese Medicine (TCM), and is based on the concept of ‘Qi’ (pronounced ‘chee’) — energy that flows through the body via pathways called meridians. The procedure involves inserting hair-thin, sterile needles into specific points on the body.4

These needles activate nerve pathways that run to the brain and spinal cord, triggering the release of your body’s natural painkillers. Acupuncture also signals the hypothalamus and pituitary gland, the master control centers for hormones and immune function.5

Understanding how acupuncture works is important if you’re curious about its role in critical care. You’re about to learn why this ancient therapy is gaining attention as a supportive option for ICU patients.

Acupuncture Could Hold the Key to a Speedy Recovery

A mini-review published in Frontiers in Neurology6 examined whether acupuncture can help ill patients recover more quickly in ICUs. The authors reviewed randomized controlled trials, systematic reviews, and mechanistic studies to evaluate their strengths and limitations.7 They focused on ICU patients who often struggle with persistent pain, delirium, muscle weakness, and digestive problems after prolonged stays.8

• Acupuncture reduces dependence on drugs — Acupuncture, especially electroacupuncture (EA) and transcutaneous electrical acupoint stimulation (TEAS), is increasingly used in ICU recovery care. According to their findings, these approaches may reduce the need for sedatives and pain medications, help patients come off ventilators sooner, and shorten ICU stays.

• Muscle weakness improves with acupuncture — ICU-acquired weakness (ICU-AW), which involves significant muscle loss after extended hospital stays, impacts up to 50% of patients. Trials indicate that combining acupuncture with rehabilitation enhances muscle strength scores and reduces ventilation duration by approximately two days. Some studies also reported increased muscle thickness, suggesting improved recovery prospects.9

• Delirium-free days were reported — Recent studies suggest acupuncture may help prevent and treat delirium in ICU patients by balancing brain chemicals, calming inflammation, and supporting normal circadian rhythms. Early findings show more delirium-free days and lower delirium rates, though larger studies are still needed.

• Gut health benefits add another layer — Acupuncture helps normalize gut function by easing constipation and reducing diarrhea. Studies show it can increase bowel movements, relieve opioid-related constipation, and lower diarrhea rates in patients receiving tube feeding.

• What do the researchers say? — The authors stressed that acupuncture should be viewed as an add-on, not a replacement for standard treatments. They also added that:

“Current evidence shows that it can safely and effectively reduce dependence on analgesic and sedative drugs, facilitate ventilator weaning, mitigate ICU-AW, decrease the incidence of delirium, and improve gastrointestinal function.

These benefits position acupuncture as a reproducible, low-risk, and potentially individualized adjunct, particularly valuable when conventional therapies are limited by adverse effects.

Future research should prioritize large multicenter [Randomized Controlled Trials] or RCTs, establish standardized operating procedures and dose — response frameworks, and incorporate real-world data with long-term outcome measures.”

To build on these findings, another team of researchers reviewed additional studies to determine how often acupuncture helps ICU patients manage multiple symptoms and even prevent infections.

Acupuncture as a Complement to Shock and Sepsis Care

To determine whether acupuncture’s benefits extend beyond limited studies, a team of researchers analyzed 12 clinical trials involving 682 critically ill patients.10 The systematic review, published in the Journal of Traditional and Complementary Medicine in 2023, focused broadly on ICU care, but also touched on conditions like shock and sepsis, where acupuncture might offer supportive benefits. Here’s what the evidence suggests:

• Animal studies show heart benefits — In one experiment, stimulating a nerve similar to acupuncture reduced heart strain and improved blood flow. This effect may result from calming the autonomic nervous system (ANS), which controls involuntary functions such as heart rate and blood pressure.

• Case reports hint at better blood flow — Stimulating acupoints on the legs and feet may help improve circulation in patients with shock (a life-threatening drop in blood flow). These findings are preliminary and require further research.

• Acupuncture may fight inflammation in sepsis — Sepsis is a severe infection that triggers widespread inflammation and organ stress. Studies suggest that acupuncture can lower inflammation, reduce cell damage caused by unstable molecules, and improve blood flow through tiny vessels that keep organs alive.

• Boosts immune defenses in lab tests — Electrically stimulating an acupoint below the knee increased immune cells like natural killer (NK) cells and T-cells, which help fight infections and maintain immune balance.

• Small trials show symptom improvement — Patients who received acupuncture along with standard care had lower sepsis severity scores and fewer inflammatory markers. Mortality didn’t change, but these results are encouraging for future research.

Acupuncture Framed as Whole-System Support in the ICU

A 2024 narrative review in the Eurasian Journal of Anesthesiology & Intensive Care takes a big-picture look at acupuncture in critical care. Their goal was to identify how it not only works for one symptom, but also supports the entire system during severe illness.11 The researchers examined acupuncture as a whole-body support tool, drawing on both traditional acupuncture theory and modern ICU practice. Here’s what they found:

• Acupuncture is designed to restore balance during critical illness — In the ICU, where multiple systems are under stress simultaneously, acupuncture may help stabilize the body rather than targeting a single symptom.

• Multiple ICU-related health concerns are addressed at the same time — The authors grouped acupuncture’s potential benefits into eight areas, including pain management, anxiety and stress relief, improving sleep quality, side effect reduction, respiratory problems, treatment of circulatory shock, nutritional support, and functional recovery after critical illness.

• Mental health and sleep take center stage — Anxiety and poor sleep weren’t treated as secondary issues. They’re highlighted as primary targets for acupuncture due to their impact on healing and overall well-being.

• Reducing side effects from drugs is a major benefit — By easing symptoms like pain or nausea, acupuncture could help lower medication doses, reducing risks from sedatives and opioids.

Acupuncture Can Help with Multiple Conditions

Providing support for ICU-related problems and alleviating chronic pain are just some of the health advantages associated with acupuncture. According to the World Health Organization (WHO), it also shows promise for helping improve the following conditions:12

Neurological and pain-related conditions
Internal and digestive disorders
Women’s reproductive health
Other conditions

Headaches
Dysentery, acute bacillary
Dysmenorrhea
Allergic rhinitis (including hay fever)

Facial pain (including craniomandibular disorders)
Epigastralgia (peptic ulcer, gastritis, gastrospasm)
Induction of labor
Depression (including depressive neurosis and post-stroke depression)

Neck pain
Biliary colic
Malposition of fetus
Adverse reactions to radiotherapy and/or chemotherapy

Knee and back pain
Renal colic

Sciatica
Morning sickness

Stroke
Leukopenia

Tennis elbow
Hypertension

Sprain
Hypotension

Rheumatoid arthritis
Nausea and vomiting

Pain in dentistry (including dental pain and temporomandibular dysfunction)

Postoperative pain

Thinking About Trying Out Acupuncture?

If you’re dealing with back pain or other nagging issues, acupuncture might be a natural way to find relief. It’s safe, effective, and supported by growing research — but it’s not something you can easily try at home. Ideally, acupuncture requires the help of a trained professional and needs to be done in a clean setting, using sterile, single-use needles. Here are tips to keep note of:13

1. Talk to your doctor first — Before booking your first session, check in with your primary care doctor. They’ll review your health history and make sure acupuncture is safe for your situation, especially if you’re pregnant, on blood thinners, or have cancer or a bleeding disorder.

2. Look for a licensed expert — In the U.S., choose someone with the credential LAc, short for licensed acupuncturist. This means they’ve passed national exams or met your state’s training requirements. If you’re outside the U.S., check with your local health board or traditional medicine council for certified providers.

3. Know what to expect at your visit — A typical acupuncture session lasts about an hour. Your first visit might run longer because you’ll discuss your symptoms and goals. The needling part usually takes 30 to 40 minutes, and you’ll rest quietly during that time.

4. Pay attention to how you feel afterward — Some people notice immediate results after one session, while others may need several. It’s common to feel sleepy, relaxed, or even more alert right after. You might also notice better sleep, digestion, or mood over time — your body will respond in its own way.

If you want to learn more about how it works, read, “Study Reveals Previously Unknown Mechanism Behind Acupuncture’s Ability to Reduce Pain.”

Not a Fan of Needles? Here’s How You Can Still Try Acupuncture

Acupuncture involves more than just needles — methods like electricity, lasers, and acupressure can also stimulate acupuncture points. For example, cancer patients receiving radiotherapy experienced reduced nausea and better sleep and mood, regardless of whether they received real or simulated acupuncture.

One popular needle-free technique is Emotional Freedom Technique (EFT), also called psychological acupressure. EFT involves tapping specific meridian points with the fingertips while focusing on a problem and voicing positive affirmations.14 This process helps clear emotional blocks and restore balance in your body’s energy system, which is essential for healing and overall well-being. You can practice EFT on your own, but for better results, working with a skilled practitioner is recommended.

Drug-Free Therapies That Support ICU Recovery

Acupuncture isn’t the only tool that helps the body heal without relying on more medications. ICU patients often deal with pain, sleep disruption, anxiety, and muscle weakness — issues that aren’t always solved with pharmaceutical interventions alone. You can also try out:

• Mindfulness practices — Practices like focused attention meditation can help dial down pain intensity. These techniques change how the brain interprets pain signals, offering relief with virtually no side effects.

•  Massage therapy — Massage has been shown to ease muscle tension, reduce anxiety, and improve sleep in patients recovering from surgery or critical illness. It’s a gentle, noninvasive option that may improve circulation and reduce discomfort associated with long-term bed rest.

• Music therapy — Live or recorded music — especially when personalized to the patient — has been shown to reduce ICU-related anxiety, lower blood pressure, and help calm patients during mechanical ventilation. Music stimulates brain areas involved in healing and relaxation, making it a powerful complement to acupuncture and other sensory-based therapies.

• Post-ICU lifestyle habits that help with recovery — After ICU discharge, implementing healthy lifestyle habits is vital to support the healing process. Here are important considerations to remember:

◦ Swap seed oils for stable fats — Too much linoleic acid (LA) from oils like soybean, corn, and sunflower drives chronic inflammation. Reducing LA to below 5 grams per day may support mitochondrial health and reduce oxidative stress in recovery. Cut out vegetable oils and choose stable fats like ghee or beef tallow.

If you want to take the guesswork out of seed oils, I recommend signing up for the Mercola Health Coach app, which is due out shortly. Its Seed Oil Sleuth feature will help you track your LA intake automatically.

◦ Eat more omega-3s from clean sources — Krill oil or wild-caught fish like Alaskan salmon help cool inflammation and protect cells. These fats support recovery of the heart, brain, and immune system after illness or trauma.

◦ Get regular, safe sun exposure — Sunlight boosts vitamin D, which plays a role in immune function and pain sensitivity. Just 15 to 30 minutes a day can help rebalance circadian rhythms and mood after hospitalization. However, make sure to eliminate LA from your diet for at least four to six months before getting peak midday sun exposure. Read “Beyond Vitamin D Production — How Sensible Sun Exposure Supports Overall Health” for more information.

Acupuncture isn’t here to replace modern medicine — it’s here to help the body remember how to heal. In the ICU, machines and medications keep patients stable, but recovery begins when balance returns. Even when illness drains strength, sleep, and clarity, acupuncture offers steady hope: it calms the nervous system, eases stress and pain, and creates the quiet conditions where healing can begin again.

Frequently Asked Questions (FAQs) About How Acupuncture Supports ICU Recovery

Q: What is acupuncture, and how does it work?
A: Acupuncture is a natural therapy that involves stimulating specific points on the body, usually with thin, sterile needles, to promote healing. It is based on the flow of ‘Qi’ (pronounced chee), or life energy. When Qi is blocked, pain and illness can develop. Acupuncture helps restore that flow, reducing pain, enhancing sleep, and supporting the immune system, all by activating the body’s own healing response.

Q: How can acupuncture help with inflammation and sepsis in ICU patients?
A: Studies suggest acupuncture may reduce inflammation, oxidative stress, and tiny blood vessel damage seen in sepsis, while supporting immune balance. Small trials found lower sepsis severity scores, though it does not replace standard infection treatment.

Q: What ICU problems can acupuncture support at the same time?
A: Reviews report acupuncture may support pain control, anxiety and stress relief, sleep quality, reduced medication side effects, breathing support, circulation and immune function, digestion and nutrition, and physical recovery during critical illness.

Q: What role does EFT play in ICU-friendly acupuncture care?
A: Emotional Freedom Techniques (EFT) use fingertip tapping on acupuncture points to calm the nervous system and release emotional tension. It’s a needle-free option that offers many of acupuncture’s benefits for patients uncomfortable with or ineligible for needles.

Q: What lifestyle changes support drug-free recovery after ICU discharge?
A: Reducing seed oils, consuming clean omega-3s, and getting safe sunlight can decrease inflammation, aid immune repair, and restore your body’s rhythm — all without needing additional medications.

Weekly Health Quiz: Glyphosate’s Dirty Secret, Secrets to Better Brain Health, and Brain Rot Basics

1 What is glyphosate’s primary role in conventional agriculture?

Killing weeds by disrupting plant growth pathways
Glyphosate is a broad-spectrum herbicide designed to kill plants by blocking a metabolic process essential for their growth. Learn more.
Preventing insect infestations in crops
Increasing the vitamin content of grains
Speeding up seed germination in organic farms

2 What is a risk of excess high-intensity exercise?

Sleep quality may suffer because of extra energy
Metabolism may slow down, depending on genetics
Social anxiety may worsen especially for younger people
Mitochondria and glucose control get disrupted
Extreme training can shut down mitochondria and disrupt blood sugar control. Learn more.

3 What mainly changes in your brain after lots of short-form video exposure?

Language skills and creativity
Sense of humor and optimism
Impulse control and stress regulation
Short-form video habits can also affect your attention aside from your self-control, and how your brain regulates stress. Learn more.
Hand-eye coordination and reflexes

4 How long does it take to see improvements in liver health from regular exercise?

Within one to two weeks of starting activity
After several years of consistent training
Only once major weight loss occurs
Within eight to 12 weeks of consistent exercise
Studies show liver fat reduction usually appears within eight to 12 weeks, while programs lasting six months or longer deliver stronger, longer-lasting metabolic benefits. Learn more.

5 Which factor receives little research funding despite being a major driver of heart disease risk?

Genetic cholesterol disorders
Environmental and endothelial damage
Pollution, lead exposure, chronic stress, and vessel damage drive heart disease risk but attract little funding because they cannot be patented or monetized like drugs. Learn more.
Dietary cholesterol intake and monitoring
Optimal statin dosing strategies

6 Why did Europe release its first clinical guide for photobiomodulation (PBM) in cancer care?

To standardize supportive light-based care in oncology
A clinical guide provides consistent treatment standards, making it easier for cancer centers to use PBM safely and effectively across Europe. Learn more.
To replace chemotherapy with light-based treatments
To limit PBM use to experimental research only
To regulate cosmetic light therapy clinics

7 Where does Big Food concentrate much of its marketing?

Whole food co-ops and local markets
Concentrated animal feeding operations (CAFOs)
Ultraprocessed foods aimed at children
Big Food targets children by marketing ultraprocessed snacks as fun, normalizing poor nutrition early. Learn more.
Public health clinics and nutritionists

 

Test Your Knowledge with
The Master Level Quiz

1 Why should regulatory claims about glyphosate safety be questioned?

Key studies with secret industry backing were retracted
Confidence in glyphosate safety is weakened when key studies are retracted for ethical reasons and hidden industry ties. Learn more.
Regulators have banned all research on glyphosate for profit motives
Organic farmers control most of the published studies
Safety claims are based only on animal testing and not human consumption

2 Why is it hard to get much thymoquinone from black cumin seed oil?

The oil is hard to find
Thymoquinone is destroyed by cooking
There’s very little thymoquinone in the oil
Thymoquinone is the main beneficial compound in black cumin seed oil, but only tiny amounts are present in the oil. Learn more.
Most brands add sugar, which disrupts the chemical makeup

3 What is one effective way to reduce glyphosate exposure?

Choosing organic or regeneratively farmed foods
Eating organic or regeneratively farmed foods helps lower glyphosate exposure by avoiding crops treated with herbicides. Learn more.
Rinsing all produce with hot water to remove residue
Avoiding all fresh fruits and vegetables sold in grocery stores
Taking daily vitamin supplements to increase antioxidant effectiveness

4 Which activity is most reliable for long-term brain health?

Heavy weightlifting
Daily sprint intervals
Marathon training
Regular moderate walking
Moderate, consistent walking is linked to slower brain decline and fewer metabolic problems. Learn more.

5 Which is a recommended way to avoid per- and polyfluoroalkyl substances (PFAS) in cosmetics?

Check labels for “perfluoro-” or “polyfluoro-”
Checking for “perfluoro-” or “polyfluoro-” on labels is the most direct way to avoid per- and polyfluoroalkyl substances (PFAS) in cosmetics. Learn more.
Choose only fragrance-free beauty products
Wash your face more often with cold water
Buy products labeled “hypoallergenic”

6 What opportunistic pathogen often rises in the gut after a colonoscopy?

Bacteroides
Lactobacillus
Firmicutes
Proteobacteria
Proteobacteria thrive when the gut is disrupted, quickly taking advantage of higher oxygen and stress after procedures like colonoscopies. Learn more.

7 Which approach is most effective for rebuilding focus?

Relying on willpower alone
Ignoring phone use and multitasking
Creating focus blocks
Changing your environment and setting daily focus periods helps restore attention better than relying on willpower. Learn more.
Taking daily memory supplements

8 Why do vision problems often appear before heart symptoms?

Large arteries handle stress longer than small vessels in the body
Eyesight conditions need more time to develop than chest pain
Heart and eye symptoms always appear together
Small eye vessels show damage from poor blood flow sooner
Tiny blood vessels in the eyes are affected by poor circulation before larger heart arteries show problems. Learn more.

9 How many Americans are affected by Type 2 diabetes?

Fewer than 5 million
About 8 million
Nearly 18 million
Over 38 million
More than 38 million Americans have Type 2 diabetes, and the number keeps rising. Learn more.

10 Which combination of exercise produces the strongest improvements for fatty liver disease?

Stretching, flexibility exercises, and some calisthenics
Aerobic exercise combined with resistance training
Combining aerobic and resistance exercise improves fat burning, insulin signaling, and blood sugar regulation more effectively than either exercise type alone. Learn more.
Resistance training without cardiovascular activity
Light walking performed a few times per week

11 Which kind of fat is most strongly linked to low vitamin D levels?

Visceral fat
Visceral fat, stored deep around organs, has the strongest association with low vitamin D levels. Learn more.
Subcutaneous fat
Fatty acids
Neck fat

12 Which neurotransmitter helps with memory, attention, learning, and emotional regulation?

Dopamine
Acetylcholine
Acetylcholine supports memory, attention, learning, and mood by helping nerve cells communicate. Learn more.
Serotonin
GABA

13 Which substance found in plaques explains why clots resist breaking down?

Low-density lipoprotein (LDL) or bad cholesterol
Red blood cells
Lipoprotein A
Lipoprotein A helps patch artery damage but makes clots harder to dissolve, promoting plaque buildup and raising heart attack risk. Learn more.
Dietary fats

14 Which of these isn’t released by microbes from fermented foods?

Acids
Enzymes
Metabolites
Hormones
Fermented food microbes release acids, enzymes, and metabolites — but not hormones — when passing through your gut. Learn more.

15 What role does brain-derived neurotrophic factor (BDNF) play in mental health?

It slows down brain development in childhood
It raises stress hormones during anxiety
It blocks new connections between brain cells
It supports learning, mood stability, and stress resilience
BDNF helps brain cells grow and connect, promoting learning, stable mood, and the ability to handle stress. Learn more.

16 Which cancer-related complications have the strongest clinical support for photobiomodulation (PBM)?

Fatigue and nausea from chemotherapy
Oral mucositis and radiation-related skin damage
Clinical research shows PBM is especially helpful for easing pain and healing mouth sores and skin reactions caused by cancer treatment. Learn more.
Hair loss and immune suppression
Infection risk and blood cell loss

17 What hormone is commonly known as the “bonding hormone”?

Oxytocin
Oxytocin is called the “bonding hormone” because it promotes connection and lowers stress. Learn more.
Cortisol
Insulin
Adrenaline

18 What happens to the brain when someone has long-term high blood pressure?

Attention and learning get a measurable boost
More oxygen reaches all brain regions over time
Blood flow drops and memory-related areas shrink
Long-term high blood pressure reduces brain blood flow and shrinks areas critical for memory, focus, and decision-making. Learn more.
Nerves controlling relaxation become more active

19 Which of the following is not considered a real food alternative to Big Food?

EatWild.com and Local Harvest
Digital farmers market platforms
Pasture-based meat and raw dairy
National frozen meal distribution centers
Industrial frozen meal brands reflect Big Food’s model, unlike small-scale, regenerative, or farm-direct options. Learn more.

20 Overconsumption of which type of oil poses a major threat to mitochondrial and skin health?

Seed oils high in omega-6 fatty acids
Omega-6-rich seed oils impair mitochondrial energy production and increase vulnerability to sun-related skin damage when consumed in excess. Learn more.
Olive oil high in monounsaturated fats
Fish oil rich in omega-3 fatty acids
Coconut oil high in saturated fats

21 How many daily grams (g) of carbohydrates helps maintain metabolic health?

50 g
100 g
250 g
Around 250 g of carbohydrates daily supports thyroid function and lowers stress hormones, while overly low-carb intake raises cortisol and strains metabolism. Learn more.
400 g

 

Begotten by His Will With the Word of Truth: Firstfruits, Spiritual Birth, and the Calling of God

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The Biblical Light Has Come: Why December 25 Belongs to Christ — Even If He Was Born at Tabernacles

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Why Confession (and Repentance) Was Central to the Original Celtic Church

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Is It Scriptural to Use the Prayer Rope (or Rosary)?

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Prayer to Jesus in Scripture and Tradition

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The Origin and Continuity of Prayer Beads and Knots Across Christendom

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Receiving the Word: How Meditation(repetition) Makes the Word Effectual

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The Persistence of Prayer: Repetition as Faith, Not Vanity

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The Eternal Law, the New Covenant, and the Misunderstanding of Love and Liberty

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Aspartame Alters Gut Bacteria and Triggers Cancer Genes in Glioblastoma

Aspartame, the artificial sweetener used in everything from diet soda to chewable vitamins, doesn’t just sweeten your food — it alters your genetic landscape and heightens your risk of glioblastoma, one of the deadliest forms of brain cancer, according to a new study.

What’s even more concerning is that these genetic shifts were traced back to disruptions in gut bacteria. If you still believe the claims that aspartame is “harmless,” these new findings will open your eyes to just how dangerous this widely used additive is.

Aspartame Activates Brain Cancer Genes, Study Finds

A recent animal study published in Scientific Reports investigated the effects of aspartame on gene expression and gut bacteria in mice with glioblastoma. Researchers assessed whether aspartame could influence tumor progression on a molecular level, even in the absence of visible tumor growth.1

• The mice used in the study had gliomas induced by transplanting cancerous cells — These test subjects were then split into two groups. One received aspartame in their drinking water, while the control group was given plain water.

• One of the most striking findings was the activation of cancer-linked genes — The researchers discovered dramatic internal changes — particularly at the genetic and microbial level — in the aspartame-exposed group. Specifically, they observed a significant upregulation of three key genes — myelocytomatosis (MYC), cyclin-dependent kinase inhibitor 1A (CDKN1A), and transforming growth factor-β (TGFB1).

• These three genes are well-established contributors to cancer progression — MYC is an oncogene, meaning it plays a direct role in driving uncontrolled cell growth, while TGFB1 is often associated with a poor prognosis in glioblastoma due to its ability to suppress immune function and promote tumor cell survival. CDKN1A is typically involved in controlling the cell cycle, but when dysregulated, it contributes to tumor aggressiveness.

• The most unsettling part? These changes happened without any measurable increase in tumor size. That means even if your tumor isn’t growing, it could still be genetically evolving into something far more dangerous.

Aspartame Alters Your Gut Microbiota by Affecting the Gut-Brain Axis

Aspartame was accidentally discovered in 1965 and had been used in consumer products since the 1980s. Being a low-calorie sweetener that’s 200 times sweeter than regular sugar, it became widely popular among people who want to cut back on their calorie consumption. It’s now used in over 6,000 different products worldwide, including diet soda, sugar-free gum and candy, and even condiments like ketchup and salad dressings.2

However, aspartame is not as safe as it seems — in fact, it has been associated with a long list of health problems, such as obesity, headaches, and depression.3 In 2023, the World Health Organization’s International Agency for Research on Cancer (IARC) declared aspartame as possibly carcinogenic to humans4 — and now, this animal study provides stronger evidence backing up this classification.

• The changes in gene activity were traced to a powerful biological process called RNA methylation — These changes occurred specifically along the N6-methyladenosine (m6A) pathway. RNA methylation is a chemical modification of messenger RNA (mRNA), the molecule your body uses to translate DNA into proteins.
This modification acts like a dimmer switch — it fine-tunes how active a gene becomes. When aspartame exposure elevated this process, the dimmer switch turned all the way up on cancer-promoting genes.

• Aspartame increases glioblastoma risk by affecting the gut-brain axis — This is the bidirectional pathway by which your gut and brain communicate with each other. Your gut bacteria synthesize short-chain fatty acids (SCFAs) like butyrate and metabolize dietary components like tryptophan into molecules that regulate the tumor microenvironment.
When these metabolites reach tumor sites, they improve immune surveillance mechanisms and alter cellular metabolic processes to inhibit tumor growth.

• Conversely, tumors also influence gut microbial composition — Certain gut bacteria that colonize tumor tissues contribute to carcinogenesis through multiple mechanisms — they induce DNA damage, suppress the immune system’s ability to recognize tumor antigens, and disrupt vital metabolic pathways. These create conditions conducive to tumor survival and proliferation.

To put it simply, some gut bacteria produce substances that help fight cancer, while others actually help tumors grow and spread; Aspartame alters your gut to increase the growth of tumor-spreading bacteria.

• Mice fed aspartame had a significant drop in bacteria from the Rikenellaceae family — Rikenellaceae are part of a group of microbes involved in producing SCFAs, which, as mentioned above, help inhibit cancer formation. According to the study authors:

“The composition and abundance of gut microbiota, particularly the Rikenellaceae family, are closely associated with the levels of volatile fatty acids, such as acetic acid, propionic acid, and butyric acid.
Numerous findings have provided compelling evidence of a robust connection between the abundance of the Rikenellaceae family in the gut and a diverse array of metabolic health conditions, including Parkinson’s disease and nonalcoholic fatty liver disease (NAFLD).

Our study concluded that although the aspartame diet did not significantly affect tumor growth, it did induce changes in the composition of the gut microbiota, particularly a decrease in the relative abundance of the Rikenellaceae family. We speculated that gut microbiota could influence the progression of glioblastoma multiforme by gut-brain axis.”5

Previous Studies Have Associated Artificial Sweeteners with a High Risk of Cancer

There’s no doubt in my mind that artificial sweeteners like aspartame are among the most pernicious ingredients to ever make into our food supply. On the outside, swapping sugar for aspartame seems beneficial for your health, but on the contrary, this is one of the worst decisions you can make, with damaging, life-long implications.

This featured study now adds to the growing list of research linking artificial sweeteners to cancer and tumor growth. Among the most notable ones are:

• A 2006 lifespan rat study published in Environmental Health Perspectives — The researchers note that aspartame “is a multipotential carcinogenic agent, even at a daily dose of … much less than the current acceptable daily intake.”6

• A 2010 study published in the American Journal of Industrial Medicine — The research confirms that this artificial sweetener is “a carcinogenic agent in multiple sites in rodents, and that this effect is induced in two species, rats (males and females) and mice (males).”7

• A 2012 paper published in the American Journal of Clinical Nutrition — Conducted by researchers from Harvard University, the study found a positive link between aspartame intake and Non-Hodgkin lymphoma and multiple myeloma (among males), and leukemia (in both males and females).8

• A 2022 study published in PLOS Medicine — The study found a link between aspartame and acesulfame-K, another artificial sweetener, and a higher risk of breast and obesity-related cancers.9

In 2024, the nonprofit organization U.S. Right to Know released a review highlighting multiple independent studies that linked aspartame not just to an increased risk of cancer, but to multiple health problems as well. The review notes:10

“Dozens of studies have linked the popular artificial sweetener aspartame to serious health problems, including cancer, cardiovascular disease, Alzheimer’s disease, seizures, stroke and dementia, as well as negative effects such as intestinal dysbiosis, mood disorders, headaches and migraines.

Evidence also links aspartame to weight gain, increased appetite and obesity-related diseases … This evidence raises questions about the legality of marketing aspartame-containing products as ‘diet’ drinks or weight-loss products.”

Artificial Sweeteners Disrupt Your Gut Health in Many Ways

Your gut microbiome is composed of trillions of good and bad bacteria that influence various factors, such as regulating digestion, metabolism, and immune function. However, when you consume artificial sweeteners, especially on a day-to-day basis, your gut microbiome changes. Studies have found that consuming artificial sweeteners disrupts your gut’s delicate balance, which leads to a cascade of health issues.

• Aspartame blocks a gut enzyme associated with weight management — An aspartame breakdown product called phenylalanine was found to inhibit the activity of a gut enzyme called alkaline phosphatase (IAP). Previous animal studies have associated IAP with the prevention of metabolic syndrome development, as well as reducing its symptoms in those with the condition.11

• Neotame causes serious damage to the intestines and overall gut health — A relatively new artificial sweetener that’s chemically similar to aspartame, neotame not only damaged bacteria commonly found in the gut, but also led to intestinal cell death, one study reported. This sweetener also disrupted the intestinal barrier, leading to increased leakage and decreased presence of claudin-3, a protein important for cell binding. According to the study authors:12

“The study is the first to show that neotame can cause previously healthy gut bacteria to become diseased and invade the gut wall — potentially leading to health issues including irritable bowel syndrome and sepsis — and also cause a breakdown of the epithelial barrier, which forms part of the gut wall.”13

• Consuming sucralose induces gut dysbiosis and alters glucose and insulin levels — A study published in Microorganisms found that ingesting this sweetener in amounts “far lower than the suggested ADI [acceptable daily intake]”14 — for just 10 weeks was enough to induce gut dysbiosis and alter glucose and insulin levels in healthy, young adults. The sweetener affects bacteria belonging to the phylum Firmicutes, which are involved in glucose and insulin metabolism.

If you truly value your overall health, tending to your gut health is key — and one of the most significant changes you can make is to avoid artificial sweeteners.

Eliminate Aspartame (and Other Artificial Sweeteners) from Your Life

The research is clear — Aspartame isn’t harmless. It disrupts your gut microbiome, activates genes tied to tumor aggressiveness, and hijacks your cellular energy machinery. If you want to protect your body from chronic diseases and avoid a glioblastoma diagnosis, I recommend following these strategies:

1. Cut aspartame and all artificial sweeteners from your daily intake — If you’re still drinking diet sodas or using sugar-free products like flavored waters, gum, or chewable vitamins, it’s time to stop. These are common sources of aspartame. Ideally, remove all ultraprocessed foods from your diet, as many are hidden sources of artificial sweeteners.

I also advise reading labels carefully. Aspartame and other sweeteners often hide behind other names, so make sure to closely check the label of the products you buy.

2. Switch to natural sweeteners — Raw Manuka honey, maple syrup, and coconut sugar, all consumed in moderation, are some of the best choices. If you’re trying to transition off sweeteners entirely, fresh fruit is an excellent way to satisfy your cravings while keeping your blood sugar balanced.

3. Restore your gut microbiome immediately — Focus on foods that help your body rebuild a healthy microbial balance. Start with whole fruits, well-cooked vegetables, and well-tolerated, cooked starches.

Fermented foods like sauerkraut, kefir, and kimchi provide natural probiotics that help rebalance your microbiome. Collagen-rich bone broth supports the gut lining, and dietary fiber from well-tolerated fruits helps feed beneficial bacteria (but make sure your gut is in optimal condition, so the fiber will feed your good bacteria instead of the bad bacteria).

4. Don’t skimp on targeted carbohydrates — Most adults need around 200 to 250 grams of carbs per day for proper mitochondrial function. That includes the brain. Restricting carbs starves your body of energy and leads to reductive stress, which only worsens the cellular chaos tied to glioblastoma. I recommend slowly reintroducing safe carbs based on your gut’s tolerance.

5. Remove other common triggers of cellular damage — If you’re serious about disrupting the root cause of glioblastoma progression, eliminate the other big offenders that compromise mitochondrial and microbiome health. That includes seed oils, electromagnetic (EMF) exposure, xenoestrogens from plastics, and processed foods.

Frequently Asked Questions (FAQs) About Aspartame and Glioblastoma

Q: How does aspartame increase the risk of glioblastoma?
A: Aspartame alters gene activity tied to cancer progression by activating RNA methylation pathways, especially the N6-methyladenosine (m6A) pathway. This boosts the expression of genes like MYC, TGFB1, and CDKN1A, which are known to drive tumor growth and make glioblastoma more aggressive — even if the tumor itself doesn’t visibly enlarge.

Q: What role does the gut microbiome play in brain cancer development?
A: Your gut bacteria influence your brain through the gut-brain axis. Aspartame disrupts this by reducing bacteria like Rikenellaceae that help produce anticancer compounds. These microbial imbalances weaken immune surveillance and encourage tumor-supporting conditions in the brain.

Q: Are artificial sweeteners really worse than sugar?
A: Yes. While marketed as safer low-calorie options, artificial sweeteners like aspartame have been linked to cancer, metabolic dysfunction, gut damage, and disrupted gene regulation. The evidence shows these additives are not harmless alternatives and could cause long-term harm to your health.

Q: What should I do if I’ve been consuming aspartame regularly?
A: Start by eliminating all artificial sweeteners from your diet — this includes checking labels on diet sodas, flavored waters, gum, vitamins, and condiments. Then, support your gut with natural carbs, fermented foods, dextrose water, and collagen-rich broths to help rebalance your microbiome and restore gene regulation pathways.

Q: Is there a safer way to satisfy my sweet cravings?
A: Yes. Transition to moderate use of natural sweeteners like raw honey, maple syrup, or coconut sugar. Better yet, rely on whole fruits with fiber, which offer natural sweetness while supporting gut and brain health. Always prioritize food sources that feed your beneficial bacteria, not fuel disease.

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