Coca-Cola Rolling Out New Misinformation Campaign to ‘Combat Obesity’

By Dr. Mercola

A new Coca-Cola ad campaign that encourages people to come together to fight obesity is drawing fire from consumer advocates and obesity experts.1, 2

Coke says it’s trying to make consumers more aware of the healthy choice beverages Coke makes; critics say Coke is simply doing damage control.

There can be no doubt that soda is one of the primary beverages responsible for skyrocketing obesity rates. As Dr. Sanjay Gupta told CNN:3

“…the scientific community has …reached a consensus that soft drinks are the one food or beverage that’s been demonstrated to cause weight gain and obesity. And if we’re going to deal with this obesity epidemic, that’s the place to start.”

Granted, no one is forcing anyone to drink them, but there simply has not been enough public education about the dangers of excessive fructose consumption. In fact, the industry has fought tooth and nail to minimize or flat out deny these health dangers, very similar to the tobacco industry denying the risk of lung cancer..

A perfect example of this ongoing denial is Coca-Cola’s reply to the video below, The Real Bears, produced by CSPI. The company called the short-film “irresponsible” and “grandstanding” that will not help anyone “understand energy balance.”

I cannot think of any instance where you might need a soda in order to maintain correct “energy balance.” You can achieve optimal health without any added sugar or artificial sweeteners. In fact, if you want to understand energy balance, read up on how to become fat-adapted rather than being a sugar burner. This requires cutting out virtually all added sugars.
Still, their vehement refusal to accept responsibility for leading you astray does not surprise me. Just take a look at the history of Coca-Cola’s advertising, and you’ll quickly realize that this leopard is not about to change its spots anytime soon. Two sites offering this history lesson include Arandilla’s “Coca-Cola Advertising Through the Years” blog4, and NPR’s blog page5, “Vigor, Brain Power and Other Health Claims From Coke’s Advertising Past.”

Now, Coca-Cola, the leading beverage brand in the world, realizes it’s losing the information war and is trying to shift your attention to its 180 different no- and low-calorie beverages. Well, this certainly is NOT going to address the obesity problem. On the contrary, artificial sweeteners have been shown to produce even MORE weight gain than regular sugar and even high fructose corn syrup.

Coke Advocating Flawed, Outdated Calorie-Counting Advice

Evidence of just how behind-the-times Coca-Cola is, their brand new multi-million dollar campaign focuses on the sentiment that:

“…beating obesity will take action by all of us, based on one simple, common-sense fact: All calories count, no matter where they come from. …And if you eat and drink more calories than you burn off, you’ll gain weight.”6

This “conventional wisdom” has been firmly debunked by science. Not all calories count equally. And the “calories in, calories out” hypothesis for maintaining weight has equally been shown to be incorrect. It is in fact FAR more important to look at the source of the calories than counting them.

In short, you do not get fat because you eat too many calories and don’t exercise enough. You get fat because you eat the wrong kind of calories. At the end of the day, your consumption of carbohydrates, whether in the form of grains and sugars (especially fructose), will determine whether or not you’re able to manage your weight and maintain optimal health. This is because these types of carbs (fructose and grains) affect the hormone insulin, which is a very potent fat regulator. Fats and proteins affect insulin to a far lesser degree. Kudos to The Atlantic7 for calling Coca-Cola on its misleading tactics in its recent article titled, Coke’s Unconscionable New Ad:

“Coca-Cola’s latest attempt to position itself against the rising tide of concern about the role of sodas in the obesity epidemic is unconscionable, because of this statement: ‘All calories count. No matter where they come from including Coca-Cola and everything else with calories.’

For Coca-Cola to suggest that all calories are equal flies in the face of reality as best as we can determine it… Coca-Cola wants us to ignore the considerable research confirming that sugary soda is a major contributor to obesity, and that it has no nutritional value… Coca-Cola could use its considerable advertising muscle to promote healthy exercise, yes, but when it does so as a ploy to confuse the public about the dangers of its products, that’s not a public service, that’s unethical.”

The video above is from Youtube and is available to the public for information and entertainment purposes only.
Mercola.com does not own and did not produce this video.

Why Calorie Counting Doesn’t Work

Dr. Robert Lustig, an expert on the metabolic fate of sugar, explains that fructose is ‘isocaloric but not isometabolic.’ This means you can have the same amount of calories from fructose or glucose, fructose and protein, or fructose and fat, but the metabolic effect will be entirely different despite the identical calorie count. This is a crucial point that must be understood.

Fructose is in fact far worse than other carbs because the vast majority of it converts directly to FAT, both in your fatty tissues, and in your liver. And this is why counting calories does not work… As long as you keep eating fructose and grains, you’re programming your body to create and store fat.

Furthermore, research by Dr. Richard Johnson, chief of the Division of Renal Diseases and Hypertension at the University of Colorado and author of The Sugar Fix and The Fat Switch, demonstrates that large portions of food and too little exercise are NOT solely responsible for why you are gaining weight. Rather it’s fructose-containing sugars that cause obesity – not by calories, but by turning on your “fat switch,” a powerful biological adaptation that causes cells to accumulate fat in anticipation of scarcity (or hibernation). According to Dr. Johnson, based on his decades of research:

“Those of us who are obese eat more because of a faulty ‘switch’ and exercise less because of a low energy state. If you can learn how to control the specific ‘switch’ located in the powerhouse of each of your cells – the mitochondria – you hold the key to fighting obesity.”

According to Beverage Digest, soda consumption in the US has been on a steady decline since 1998.8 A recent article in The Atlantic9 shows consumption of soda “in freefall,” with US consumption having declined by 40 percent since 2003. Unfortunately, many are simply switching to no- or low-cal beverages, which Coca-Cola is now trying to boost, and quite frankly, if I had to choose between these two evils, I’d choose regular soda, as artificial sweeteners are even worse for your long-term health, and have been linked to increased weight gain when compared to calorie-containing sweeteners.

No- or Low-Cal Beverages CONTRIBUTE to Obesity Problem

While soda consumption has gone down, consumption of artificially sweetened “diet” beverages has risen in that same time, according to an October 11, 2012 report by USA Today.10 The industry has effectively convinced people that diet drinks are a healthier choice because they lack any calories. However, if you’re concerned about your weight and health, switching to artificial sweeteners is NOT a wise move.

Mounting research shows that diet soda is not a “guilt-free” treat at all. For example, two studies published in 2011 linked diet soda to poor health outcomes. In one study, people who drank two or more diet sodas a day experienced waist size increases that were six times greater than those of people who didn’t drink diet soda. A second study that found that aspartame (NutraSweet) raised blood sugar levels in diabetes-prone mice.

As you may know, your waist size is not only a matter of aesthetics, but also a powerful indicator of a build-up of visceral fat, a dangerous type of fat around your internal organs that is strongly linked with type 2 diabetes and heart disease. Your waist size is a far more accurate predictor of your heart risks than your body mass index (BMI). Nearly eight years ago, research by Sharon P. Fowler, MPH11 (who was also involved in the newer studies noted above) found that your risk of obesity increases by 41 percent for each can of diet soda you drink in a day. Furthermore, for diet soft-drink drinkers, the risk of becoming overweight or obese was:

36.5 percent for up to 1/2 can per day
57.1 percent for more than 2 cans per day

For regular soft-drink drinkers, the risk of becoming overweight or obese was:

26 percent for up to 1/2 can per day
32.8 percent for 1 to 2 cans per day
47.2 percent for more than 2 cans per day

How Decreasing Sugar Intake Can Impact Body Weight

In related news, recently published research12 shows that decreasing sugar consumption can help you lose weight. The researchers examined outcomes from 71 studies on sugar consumption and body fat. The duration of included studies ranged from two weeks to one year. According to the authors:

“In trials of adults with ad libitum diets (that is, with no strict control of food intake), reduced intake of dietary sugars was associated with a decrease in body weight (0.80 kg/1.8 lb); increased sugars intake was associated with a comparable weight increase (0.75 kg/1.7 lb).

Isoenergetic exchange of dietary sugars with other carbohydrates showed no change in body weight . Trials in children… in relation to intakes of sugar sweetened beverages after one year follow-up in prospective studies, the odds ratio for being overweight or obese increased was 1.55 (1.32 to 1.82) among groups with the highest intake compared with those with the lowest intake. Despite significant heterogeneity in one meta-analysis and potential bias in some trials, sensitivity analyses showed that the trends were consistent and associations remained after these studies were excluded.”

Skyrocketing Obesity is Related to Misleading You on Health Issues

Obesity is the result of inappropriate lifestyle choices, and unfortunately, our government has done an abysmal job at disseminating accurate information about diet and health. It’s one thing for corporations to put out misleading ads – honesty is not in the self-interest of the processed food and beverage industry. It’s another when the government falls in line with for-profit deception and becomes a propagator of corporate propaganda. And this is exactly what has happened… For example, conventional advice that is driving public health in the wrong direction includes:

Cutting calories: Not all calories are created equal, and counting calories will not help you lose weight if you’re consuming the wrong kind of calories
Choosing diet foods will help you lose weight: Substances like Splenda and aspartame may have zero calories, but your body isn’t fooled. When it gets a “sweet” taste, it expects calories to follow, and when this doesn’t occur it leads to distortions in your biochemistry that may actually lead to weight gain
Avoiding saturated fat: The myth that saturated fat causes heart disease has undoubtedly harmed an incalculable number of lives over the past several decades, even though it all began as little more than a scientifically unsupported marketing strategy for Crisco cooking oil. Most people actually need at least 50 percent of their diet to include healthful saturated fats such as organic, pastured eggs, avocados, coconut oil, real butter and grass-fed beef in order to optimize their health
Reducing your cholesterol to extremely low levels: Cholesterol is actually NOT the major culprit in heart disease or any disease, and the guidelines that dictate what number your cholesterol levels should be to keep you “healthy” are fraught with conflict of interest — and have never been proven to be good for your health

This is just a tiny sampling of the misleading information on weight and obesity disseminated by our government agencies. A more complete list of conventional health myths could easily fill an entire series of books. The reason behind this sad state of affairs is the fact that the very industries that profit from these lies are the ones funding most of the research; infiltrating our regulatory agencies; and bribing our political officials to support their financially-driven agenda through any number of legal, and at times not so legal, means.

Could Warning Labels Be Part of the Answer?

According to Dr. Harold Goldstein, executive director of the non-profit group The California Center for Public Health Advocacy (CCPHA), “43 percent of the increase in daily calories Americans consumed over the last 30 years came from sugary drinks.” The CCPHA has published a list of seven things soda makers could do to create “meaningful change,” such as13:

Cease all advertising of sugary drinks to children under 16
Add warning labels to containers stating the link between soda consumption and obesity, diabetes and tooth decay, just like cigarettes must declare its connection to lung cancer
Declare number of teaspoons of sugar the container contains, in large print
Quit marketing sports drinks as healthy beverages

You Can Avoid Becoming a Statistic

Perhaps one of the most powerful scientific discoveries to emerge in the past several years is that the old adage “a calorie is a calorie” is patently false. Furthermore, the idea that in order to lose weight all you have to do is expend more calories than you consume is also false… The research clearly demonstrates that even if you control the number of calories you eat, if those calories come from fructose, you are at increased risk of developing metabolic syndrome, or prediabetes, which includes insulin resistance, fatty liver, high blood pressure and high triglycerides.

Conventional thinking tells us that metabolic syndrome is the outcome of obesity, which is simply the result of eating too many calories and not exercising enough. However, Dr. Johnson’s research, discussed above, shows that a high fructose diet is the key to developing metabolic syndrome, and that as soon as you throw fructose into the mix, “calories in versus calories out” is no longer a functional equation.

In short, avoiding fructose in all its forms, along with other sugars, is imperative in order to avoid “flipping the fat switch” that can trigger your body to accumulate excess fat. So please, do yourself and your family a favor, and don’t get swept up in Coca-Cola’s multi-million dollar ad extravaganza. The entire campaign is based on flawed, inaccurate, misleading, and patently false conventions of thinking.

Let’s not forget: Coca-Cola spent $1.2 million to defeat California Proposition 37 last November, which would have required genetically engineered (GE) foods to be labeled as such (which could have included soda containing GE high fructose corn syrup). That, in and of itself, is proof positive that Coca-Cola has no concern for health conscious consumers.

How Innate ‘Plasticity’ of Your Brain Allows You to Improve Cognitive Performance and Prevent Age-Related Decline

By Dr. Mercola

It was once thought that any brain function lost was irretrievable. Today, research into what’s referred to as “brain plasticity” has proven that this is not the case. On the contrary, your brain continues to make new neurons throughout life in response to mental activity.

Aside from toxicity, our modern lifestyle plays a part in cognitive decline, as described by Dr. Michael Merzenich, professor emeritus at the University of California, who has pioneered research in brain plasticity for more than 30 years.

He founded the Scientific Learning Corporation in Oakland, California, and Posit Science in San Francisco; both specializing in science research into brain training software.

Dr. Merzenich’s career arose from an interest in philosophy, and a fascination with the nature and origin of the human persona and individuality, and how brain processes might account for the evolution of our individual abilities. He believed that in those who have learning disabilities, the natural progressions of these brain processes must have encountered errors.

Use It or Lose It — the Principles of Brain Plasticity

The inherent plasticity of the brain was discovered some 20 years ago, when animal models demonstrated that brain deterioration and aging was in fact reversible, provided the proper stimulus. Dr. Merzenich describes brain plasticity as follows:

“It’s simple in concept. The brain changes physically, functionally, and chemically, as you acquire an ability or as you improve an ability. You know this instinctively. Something must be changing as your brain advances, as it progresses.

Actually what it is doing is changing the local wiring, changing the details of how it’s connected. It’s also changing itself in other ways, physically, functionally, and those changes account for that improvement, or account for the acquisition of an ability.

You don’t realize it but as you acquire an ability – let’s say, the ability to read – you actually create a system in the brain that does not exist, or that’s not in place, in the non-reader. It [the ability] actually evolves in the brain.”

As Dr. Merzenich explains, your brain is designed and constructed to be stimulated and challenged, and to carefully examine, resolve and interpret your environment. During the early days of mankind’s development, keeping track of the details was imperative for survival.

Today however, we tend to try to remove ourselves from the details of life. For example, instead of keeping track of appointments and to-do lists in our head, we use electronic gadgets with reminder features. Our streets are paved and lit, requiring virtually no attention to navigate from one location to another. And if you don’t sufficiently challenge your brain with new, surprising information, it eventually begins to deteriorate.

“Generally, by the third or fourth decade in life, you’re in decline,” Dr. Merzenich says. “One of the things that happens across this period is that you go from a period of the acquisition of abilities to largely using those abilities that have been acquired earlier in life. By that I mean to say, the fundamental skills that you apply in your profession or in your everyday life are things you master, and you’re doing them without thought.

To a large extent, you’re operating most of your day without really being consciously engaged in the things you’re doing… I’ve gone without really thinking very much about the physical acts of driving. I’m substantially disengaged.

This has been contributed to substantially by modern culture. Modern culture is all about taking out surprises… to basically reduce the stimulation in a sense on one level, so that we could engage ourselves in sort of an abstract level of operations. We’re no longer interested in the details of things. We’re no longer interested in resolving the details of what we see or hear or feel, and our brains slowly deteriorate.”

Contributing Factors to Cognitive Decline, and How to Counteract it

With age, brain researchers have found that there’s an increase in “chatter” in your brain. Dr. Merzenich explains:

“Your brain becomes less precise in how it’s resolving information as you’re operating and listening in language, as you’re operating in vision, or as you’re operating in controlling your actions. And we actually see these other noise processes through the brain as you age. In fact, we can correlate those changes quite directly with the slowing down of your processing.

You know, every older person is slower in their actions, slower in their decisions, and less fluent in their operations than when they’re younger. They’re slower because the brain basically is dealing with information in a fuzzier and degraded form.”

What research into brain plasticity shows us is that by providing your brain with appropriate stimulus, you can counteract this degeneration. A key factor or ingredient necessary for improving brain function or reversing functional decline is the seriousness of purpose with which you engage in a task. In other words, the task must be important to you, or somehow meaningful or interesting — it must hold your attention. Rote memorization of nonsensical or unimportant items will not stimulate your brain to create new neurons.

Dr. Merzenich has been instrumental in the development of a kind of environment — a computer-based brain training program that can help you sharpen a range of skills, from reading and comprehension to improved memorization and more. The program is called Brain HQ1.

“There are some very useful exercises in there that are for free, and you can actually drive improvements, for example, in brain speed, in the accuracy, with which the brain represents information in detail,” he says.

“Basically, what you’re doing is reducing the chatter, the noisiness of the process of your brain. That impacts your capacity, for example, to record that information; to remember it. Because when the information is in its degraded form, when it’s fuzzy, when it’s imprecise, all of the uses of it – like your brain makes basically – are degraded.”

Who Can Benefit from This?

Everybody’s brain is plastic, including yours, so no matter what your age or current level of brain function, your brain can improve to some degree or other. Dr. Merzenich specializes in children, primarily those with learning disabilities or impairments. But seniors and adults of all ages are also starting to use the program, and all age groups have been found to reap significant rewards.

In children operating in the 10th percentile of academic performance are commonly able to improve their scores to the middle or average level with 20-30 hours of intensive computer-based training.

“Now, that’s a big difference for the child,” he says. “It carries the child from a position which is at the bottom of the class, on the average, to be somewhere in the middle of the class. And that gives a child a chance to excel in school.”

Careful control studies in seniors have also been done. After 40 hours of computer-based training, the average improvement in cognitive performance across the board was 11 years. Meaning, if you were 70 years old, after 40 hours of brain training, your cognitive abilities could operate like that of a 59-year old. The same, and in some cases greater, effect can be found in 40-50-year olds using the program.

How to Implement a Brain Training Program

So, how does such a training program work, and what’s the optimal way to implement it in order to maximize the benefits?

“One of the great advantages that we have is that there’s a very large body of scientific information that informs us about the optimum,” Dr. Merzenich says. “It comes from understanding, on a scientific level, the basis of what controls brain change. We know how the machine operates to control brain change. We know that you have to be engaged attentively, and in a sense that the more attentively focused you are, the more positively enabling machine the brain is when turned on.

We know that rewards have to occur, or information or feedback about how you’re doing have to occur, in a specific way to drive the optimum changes in the brain… the way difficulties change in the task are crucial for driving changes with highest proficiency.

One simple thing we do is to [continually] adjust the difficulty level of the task, so that the child is at a level in which they get most things correct but they’re capable of error. Because only when you’re in this demanding situation, only when it matters to the brain, does the machinery turn on to change the brain. We actually regulate this, and as a child progresses session by session, day by day, they notch up their performance to higher and higher and higher and higher and higher levels.”

Ideally, it would be wise to invest at least 20 minutes a day. But no more than five to seven minutes is to be spent on a specific task. When you spend longer amounts of time on a task, the benefits weaken. According to Dr. Merzenich, the primary benefits occur in the first five or six minutes of the task.

You can typically improve yourself to the highest practical or possible level in anywhere between five to a dozen brief sessions of seven or eight minutes each. Again, having a sense of purpose is crucial.

“When it matters to you, you are going to drive changes in your brain,” he explains. “That’s something always to keep in mind. If what you’re doing seems senseless, meaningless, if it does not matter to you, then you’re gaining less from it.”

Dr. Merzenich developed a website, Brain HQ, to help take advantage of the brain’s ability to repair.The Brain HQ website has many different exercises designed to improve brain function and it also allows you to track and monitor your progress over time. While there are many similar sites on the web, Brain HQ is one of the oldest and most widely used.

How Your Daily Lifestyle Can Improve Your Brain Function

Aside from engaging in a computer-based brain exercise program, Dr. Merzenich lists several things you can do on a daily basis, as part of your day-to-day lifestyle, to help maintain optimal brain fitness:

Get 15-30 minutes of physical exercise each day, when exercising, think about using your brain to control your actions. That means, skip the iPod and instead take in the details of your environment.

“Reconstruct it in your mind. Basically, we are constructed to take in the details of our physical environments, and to interpret and reconstruct them. That’s a critical form of exercise for us basically to refine our navigational skills and abilities in this sense – to basically look at the landmarks, to look at the details, to record them in detail,” he says.

Secondly, look for and take note of surprises in your environment. “If you walk across the landscape and are paying attention, you cannot take a walk for 15, 20, or 30 minutes without being surprised,” he says. “And the brain loves surprises, because surprises mean that they must be engaged to interpret what they mean.”

Lastly, pay attention to your physical body. “You should feel yourself again. When’s the last time you actually thought about the feelings of you movements?”

Spend about five minutes every day working on the refinement of a specific, small domain of your physical body. Dr. Merzenich explains:

“That is to say, move in a very variable and controlled way – variable in speed, variable to reach a target, for example, with your big toe or your little finger. Do that every day. I do that in a systematic way, because I’m trying to maintain the fidelity of the neurological control movement. I know that I’m very much thinking about the feeling in my movements as I do that.”

Find ways to engage yourself in new learning as a continuous aspect of your life, such as taking on new hobbies, learning new skills
Stay socially engaged
Practice “mindfulness,” in which you’re attentively focusing on the world around you again, as if you’re seeing it for the first time.

“Look at the wonder in the flower. Look with curiosity again at the movements of the lizard. Engage in the details of the world and in life. Associate what you hear with what you feel on your skin,” he suggests. “It’s incredibly important that you engage the brain and all of its details of how it’s drinking in information, because this again relates to the fidelity with which it will represent it for all of its operations.”

Nutrition and Brain Health

Another factor that cannot be overlooked is your diet. Foods have an immense impact on your brain, and eating whole foods as described in my nutrition plan will best support your mental and physical health. Just like exercise, avoiding sugar (particularly fructose) and grains will help normalize your insulin levels.

This is an important aspect, as sugar causes chronic inflammation that disrupts your body’s normal immune function and can wreak havoc on your brain. But sugar also suppresses BDNF, which is important for proper memory function, and appears to play a significant role in depression as well. At least we know that BDNF levels tend to be critically low in people with depression, and some animal models have suggested low BDNF levels may actually be causative.

The medical literature is also showing that coconut oil can be of particular benefit for brain health, and anecdotal evidence suggests it could be very beneficial in the treatment of Alzheimer’s disease. Ketone bodies have been found to feed your brain and prevent brain atrophy. It may even restore and renew neuron and nerve function in your brain after damage has set in. Ketones are what your body produces when it converts fat (as opposed to glucose) into energy, and a primary source of ketone bodies are the medium chain triglycerides (MCT) found in coconut oil. Other dietary recommendations to preserve and improve your brain health include the following:

Optimize your vitamin D levels through safe sun exposure, a safe tanning bed and/or vitamin D3 supplements.
Take a high-quality animal-based omega-3 fat. I recommend consuming high quality krill oil to meet the optimal amount of omega-3 fats needed to achieve good health and fight cognitive decline
Avoid processed foods and sugars, especially fructose — Excessive sugar and grain consumption are the driving factors behind insulin resistance, and the strategies that protect your brain are very similar to those for avoiding diabetes. There is simply no question that insulin resistance is one of the most pervasive influences on brain damage, as it contributes massively to inflammation, which will prematurely degenerate your brain.
Ideally, you’ll want to restrict your total fructose consumption to below 25 grams a day. This includes refraining from eating too many fruits, if you normally eat a lot of them. If you consume more than 25 grams a day of fructose you can damage your cells by creating insulin and leptin resistance and raising your uric acid levels.
Avoid grains – Even whole, organic grains will convert to sugar in your body and spike your insulin levels.
Avoid artificial sweeteners – Aspartame, for example, is an excitotoxin that can literally destroy your brain cells. There are many studies showing the dangers of aspartame.For example, one study published in 20082 concluded that excessive aspartame ingestion might cause certain mental disorders, as well as compromised learning and emotional functioning.
Avoid soy — Unfermented soy products are another common food that should be avoided if you want to maintain healthy brain function.

One well-designed epidemiological study linked tofu consumption with exaggerated brain aging. Men who ate tofu at least twice weekly had more cognitive impairment, compared with those who rarely or never ate the soybean curd, and their cognitive test results were about equivalent to what they would have been if they were five years older than their current age. What’s more, higher midlife tofu consumption was also associated with low brain weight. Shrinkage does occur naturally with age, but for the men who had consumed more tofu showed an exaggeration of the usual patterns you typically see in aging.
Dr. Kaayla Daniel has written an excellent book, The Whole Soy Story, which covers the health dangers of soy in great depth and I highly recommend it to anyone still under the illusion that soy is a health food.

Artificial Sweeteners Cause Greater Weight Gain than Sugar, Yet Another Study Reveals

By Dr. Mercola

Are you using artificial sweeteners and opting for low-cal “diet” foods in an effort to control of your weight?
If so, you may be surprised to learn that research has repeatedly shown that artificial no- or low-calorie sweeteners are anything but good news for weight loss… Contrary to popular belief, studies have found that artificial sweeteners such as aspartame can:

Stimulate your appetite
Increase carbohydrate cravings
Stimulate fat storage and weight gain

Now, yet another study1 has been published showing that saccharin and aspartame cause greater weight gain than sugar.
The belief that artificially sweetened foods and beverages will help you lose weight is a carefully orchestrated deception. So if you are still opting for “diet” choices for this reason, you are being sorely misled. Ditto for diabetics, as recent research has shown aspartame also worsens insulin sensitivity.
The fact that these are still being promoted as “diet” flies in the face of any rational behavior. One wonders why the FTC doesn’t come down like a ton of bricks on these companies for massively fraudulent marketing.

New Study Negates Weight Management Claims of Artificial Sweeteners

The featured study, published in the January 2013 issue of the journal Appetite2, was done by a Brazilian research team with the Faculty of Medicine of the Federal University do Rio Grande do Sul. Rats were fed plain yogurt sweetened with either aspartame, saccharin, or sugar, plus their regular rat chow, for 12 weeks.

“Results showed that addition of either saccharin or aspartame to yogurt resulted in increased weight gain compared to addition of sucrose, however total caloric intake was similar among groups,” the researchers write.3

The reason for the similar calorie consumption between the groups was due to increased chow consumption by the rats given artificially sweetened yoghurt. This type of compensation has been found in previous studies4 as well, indicating that when your body gets a hit of sweet taste without the calories to go with it, it adversely affects your appetite control mechanisms, causing increased food cravings. The authors concluded that:

“Greater weight gain was promoted by the use of saccharin or aspartame, compared with sucrose, and this weight gain was unrelated to caloric intake. We speculate that a decrease in energy expenditure or increase in fluid retention might be involved.”

You Actually Gain Weight by Using “Artificial Sweeteners

A 2010 scientific review published in the Yale Journal of Biology and Medicine (YJBM)5 discussed the neurobiology of sweet cravings and the unexpected effect of artificial sweeteners on appetite control. It cites several large scale prospective cohort studies that found positive correlations between artificial sweetener use and weight gain, which flies in the face of “conventional wisdom” to cut calories in order to lose weight. For example:

“The San Antonio Heart Study6 examined 3,682 adults over a seven- to eight-year period in the 1980s. When matched for initial body mass index (BMI), gender, ethnicity, and diet, drinkers of artificially sweetened beverages consistently had higher BMIs at the follow-up, with dose dependence on the amount of consumption. Average BMI gain was +1.01 kg/m2 for control and 1.78 kg/m2 for people in the third quartile for artificially sweetened beverage consumption.

The American Cancer Society study7 conducted in early 1980s included 78,694 women who were highly homogenous with regard to age, ethnicity, socioeconomic status, and lack of preexisting conditions. At one-year follow-up, 2.7 percent to 7.1 percent more regular artificial sweetener users gained weight compared to non-users matched by initial weight… Saccharin use was also associated with eight-year weight gain in 31,940 women from the Nurses’ Health Study8 conducted in the 1970s.”

Experiments have found that sweet taste, regardless of its caloric content, enhances your appetite. Aspartame has been found to have the most pronounced effect, but the same applies for other artificial sweeteners, such as acesulfame potassium and saccharin.
The reason why glucose or sucrose (table sugar) tends to lead to lower food consumption compared to non-caloric artificial sweeteners is because the calories contained in natural sweeteners trigger biological responses to keep your overall energy consumption constant. This was again evidenced in a study9 published last year, which concluded that:

“The results support the hypothesis that consuming non-caloric sweeteners may promote excessive intake and body weight gain by weakening a predictive relationship between sweet taste and the caloric consequences of eating.”

In essence, real sugar allows your body to accurately determine that it has received enough calories, thereby activating satiety signaling. Without the calories, your appetite is activated by the sweet taste, but as your body keeps waiting for the calories to come, sensations of hunger remain.

“Human research must rely on subjective ratings and voluntary dietary control. Rodent models helped elucidate how artificial sweeteners contribute to energy balance. Rats conditioned with saccharin supplement had significantly elevated total energy intake and gained more weight with increased body adiposity compared to controls conditioned with glucose. Saccharin-conditioned rats also failed to curb their chow intake following a sweet pre-meal…

Increasing evidence suggests that artificial sweeteners do not activate the food reward pathways in the same fashion as natural sweeteners… Lastly, artificial sweeteners, precisely because they are sweet, encourage sugar craving and sugar dependence… Unsweetening the world’s diet may be the key to reversing the obesity epidemic,” the YJBM review states.10

That last statement is probably the most accurate conclusion there is. Americans in particular are addicted to the flavor sweet, which appears to trigger a complex set of biological systems, pathways, and mechanisms that in the end leads to excess weight gain whether that flavor comes loaded with calories or not.

Another Oft-Ignored Mechanism Driving Weight Gain from Artificial Sweeteners

Another reason for aspartame’s potential to cause weight gain is because phenylalanine and aspartic acid – the two amino acids that make up 90 percent of aspartame — are known to rapidly stimulate the release of insulin and leptin; two hormones that are intricately involved with satiety and fat storage. Insulin and leptin are also the primary hormones that regulate your metabolism.
So although you’re not consuming calories in the form of sugar, aspartame can still raise your insulin and leptin levels. Elevated insulin and leptin levels, in turn, are two of the driving forces behind obesity, diabetes, and a number of our current chronic disease epidemics. Over time, if your body is exposed to too much leptin, it will become resistant to it, just as your body can become resistant to insulin, and once that happens, your body can no longer “hear” the hormonal messages instructing your body to stop eating, burn fat, and maintain good sensitivity to sweet tastes in your taste buds.
What happens then?
You remain hungry; you crave sweets, and your body stores more fat. Leptin-resistance also causes an increase in visceral fat, sending you on a vicious cycle of hunger, fat storage and an increased risk of heart disease, diabetes, metabolic syndrome and more.
Additionally, large doses of phenylalanine can lower important neurotransmitters like sero­tonin,11 which also influences satiety. Decreased serotonin levels reduce feelings of satiety, which can then lead to over-eating or binge eating. In the end, the research tells us that artificial sweeteners are nothing more than a pipe dream when it comes to being a dieter’s aid, because contrary to what the marketing campaigns claim, low- or no-calorie artificial sweeteners are more likely to help you pack on the pounds than shed them.

What’s the Answer for Stubborn Weight Gain?

The first thing you need to understand is that counting calories is typically useless for weight loss. This is because calories are NOT created equal, and will not have identical effects on your weight or health. And, as reviewed above, trying to fool your body with artificial sweeteners devoid of calories is not the answer. In fact, it will likely make matters worse.
Secondly, it’s important to realize that the preferred fuel for your body is fat, not carbohydrates. Switching from a carb-based diet to a fat- and protein-based diet will help rebalance your body’s chemistry, and a natural side effect of this is weight loss, and/or improved weight management once you’re at an ideal weight. One explanation for this is that you don’t really get fat from eating too much and exercising too little. Nor do you get fat from eating fat.
In fact, there’s reason to believe that most people’s health would benefit from having:

As much as 60-70 percent healthful fats in their diet, and
No more than one gram of protein per kilo of lean body mass or about 0.5 grams of protein per pound of lean body mass. (Can be increased by 25 percent if pregnant or aggressively exercising). To determine your lean body mass, calculate your body fat percentage and subtract that from 100. So if you are 20 percent body fat you would have 80 percent lean body mass. Then, multiply that times your current weight to get lean body mass in kilos or pounds

Dr. Richard Johnson’s latest book, The Fat Switch, dispels many of the most pervasive myths relating to diet and obesity. He discovered the method that animals use to gain fat prior to times of food scarcity, which turned out to be a powerful adaptive benefit. His research showed that fructose activates a key enzyme, fructokinase, which in turn activates another enzyme that causes cells to accumulate fat. When this enzyme is blocked, fat cannot be stored in the cell.
Interestingly, this is the exact same “switch” animals use to fatten up in the fall and to burn fat during the winter. Fructose is the dietary ingredient that turns on this “switch,” causing cells to accumulate fat, both in animals and in humans.
In essence, overeating and excess weight could be viewed as a symptom of the wrong proportion of macronutrients. You’re simply not feeding your body the right fuel. It’s not necessarily the result of eating too many calories, per se, but rather getting your calories from the wrong sources. In simple terms, when you consume too many sugars and carbs, you set off a cascade of chemical reactions in your body that makes you hungry and leaves you craving for sweets.
Even if you have the highest quality raw and organic foods, if you have a non-optimal combination with identical calories, you will likely gain weight. So listen to your body and if you are one of the two-thirds of people who are overweight, seriously consider radically reducing your carbs and replacing them with fibrous vegetables, lowering your protein levels to the quantity discussed above, and replacing those missing calories with healthy fats from coconut oil, olives, olive oil, avocado, pastured grass fed butter, and nuts. You can also try intermittent fasting, which will give you a radical jumpstart in your ability to normalize your weight.

Another Health Fraud — “Fat-Blocking” Soda

By Dr. Mercola

“Pepsi Special” is the latest “healthy soda” to hit the market, this time in Japan. Infused with dextrin, a type of fiber that’s popular in fiber supplements in the U.S., Pepsi Special is being marketed as a “fat-blocking soda,” as it claims to help reduce your body’s absorption of fat.

How Can Soda Claim to Help You Absorb Less Fat?

Pepsi’s Japanese partner, Suntory Holdings Limited, is reportedly basing their claim, in part, on a 2006 study that found rats fed dextrin absorbed less fat from their food,1 and Japan’s National Institute of Health and Nutrition now allows it to bear the designation as a “food for specified health use.”
These are foods that are meant to be consumed “by people who wish to control health conditions, including blood pressure or blood cholesterol.”2 But can soda really be healthy?
Not likely.
Pepsi Special is far from a health food. Adding fiber to a disastrous combination of high fructose corn syrup, phosphoric acid, caffeine and coloring does not make it good for you. But it may “fool” some people into thinking it does, which could make them drink even more of it, further damaging their health.
Soda is a leading contributor to the rising rates of obesity, diabetes, heart disease and other chronic diseases facing much of the developed world, and any claims to the contrary are dangerously misleading. As Dr. Walter Willett, chair of nutrition at the Harvard School of Public Health, told Time:3

“Unless Pepsi can provide data from controlled studies in humans to the contrary, their claim should be regarded as bogus and deceptive.”

Pepsi’s Eager to Cash In on Health-Conscious Consumers

Remember Pepsi Raw, which was introduced in the UK in 2008? This was another one of the soda company’s ridiculous creations – a concoction of sugar, caramel coloring, coffee leaf and sparkling water that was supposed to be another “healthy” version of soda.
While it had 10 percent less sugar than regular Pepsi, Pepsi Raw was simply another sugar-sweetened beverage, not a health drink. It was removed from the market just two years after its release.
Earlier this year, Pepsi Next was released. Pepsi Next claims to have 60 percent less sugar without sacrificing taste, but the secret to keeping its sweet taste comes from the use of not only high fructose corn syrup, but also THREE artificial sweeteners: aspartame, acesulfame potassium, and sucralose, all of which are linked to several dozen serious health risks.4
It’s all part of the company’s plan to beef up their share of profits from the “healthy foods” category, with reports noting they hope to boost their nutrition business from $10 billion to $30 billion by 2020.5
This is a classic corporate move. Find something that people are interested in and sell it to them even if it is deceptive and worsens their health. Most of these companies have absolutely ZERO interest for your health; they are only focused on their bottom line profits. So the age old adage is appropriate, Buyer Beware.

Is “Healthy” Soda Too Good to be True?

In a word, yes.
There’s nothing healthy about soda, even if it contains fiber or is sugar free. Drinking soda is in many ways worse for you than smoking, and it is only because of massive marketing campaigns from the industry that these sugary beverages are deemed so acceptable, including for our most vulnerable members of society – our kids.
If I asked you to quickly recall a commercial or slogan from leading soda companies, like Coca-Cola or Pepsi, chances are you’d have no trouble recalling the friendly polar bear commercials or “the real thing” logo, and if you asked your kids, they’d probably come up with a few too.
This is just the tip of the iceberg for how beverage bigwigs have gotten their products firmly embedded into the homes and psyches of millions of Americans and others worldwide. Coca-Cola, for instance, spends close to $3 billion a year on advertising. With that amount of money it’s no wonder the company has managed to hold on to its wholesome reputation.
They, and other beverage giants, are also in the habit of forming strategic alliances with ostensibly health-focused organizations that make it appear as though they are looking out for your health, which is about as laughable as Big Tobacco sponsoring a marathon. For instance, both Coca-Cola and Pepsi are sponsors or partners of the American Dietetic Association (ADA) and have featured exhibits at their annual conference.
Diet Coke has also teamed up with the National Heart, Lung, and Blood Institute (NHLBI) to raise awareness for women’s heart health program, even though Coca-Cola is one of the main retailers of sugar in the United States and it is very clear that sugar and fructose are actually leading causes in the increasing rates of heart disease.

Fructose: Soda’s Dirty Secret

The primary reason why soda is so dangerous to your health?
Fructose.
The fructose content of the high fructose corn syrup (HFCS) used in many popular soda brands has been grossly underestimated. Around 100 years ago the average American consumed a mere 15 grams of fructose a day, primarily in the form of fruit, not industrially produced isolate, which is infinitely different on a physiological level. One hundred years later, one-fourth of Americans are consuming more than 135 grams per day, largely in the form of soda.
Fructose at 15 grams a day or less is generally harmless (unless you suffer from high uric acid levels). However, at nearly 10 times that amount it becomes a major contributor to obesity and nearly all chronic degenerative diseases. Instead of consisting of 55 percent fructose and 45 percent glucose, many soda brands, including Coke, Pepsi and Sprite, contain as much as 65 percent fructose, nearly 20 percent higher than originally believed.6 Thanks to the excellent work of researchers like Dr. Robert Lustig, and Dr. Richard Johnson, we now know that fructose:

Is metabolized differently from glucose, with the majority being turned directly into fat
Tricks your body into gaining weight by fooling your metabolism, as it turns off your body’s appetite-control system. Fructose does not appropriately stimulate insulin, which in turn does not suppress ghrelin (the “hunger hormone”), doesn’t drive glucose into the cell to create satiety, and doesn’t stimulate leptin (the “satiety hormone”), which together result in your eating more and developing insulin resistance.
Rapidly leads to weight gain and abdominal obesity (“beer belly”), decreased HDL, increased LDL, elevated triglycerides, elevated blood sugar, and high blood pressure — i.e., classic metabolic syndrome.
Over time leads to insulin resistance, which is not only an underlying factor of type 2 diabetes and heart disease, but also many cancers.
Leads to a dopamine-mediated hedonistic syndrome, which causes an insatiable desire to consume more of the same, despite the broad range of adverse, even life-threatening health effects caused by excessive fructose consumption.

Diet soda, by the way, is NOT a healthy alternative, even though it’s fructose-free. People who drink diet soft drinks daily may be 43 percent more likely to suffer from a vascular event, including a stroke or heart attack,7 as well as are more likely to experience weight gain, increased waist size, diabetes and metabolic syndrome.

Warning: 5-Hour Energy Shots Linked to Deaths

If you’re thinking of ditching your soda in favor of another caffeine kick like 5-hour Energy, be warned that 13 potentially related deaths and more than 90 adverse reaction claims (including 33 hospitalizations) following its consumption have already been reported to the U.S. Food and Drug Administration (FDA). Although the product’s label does not disclose how much caffeine it contains per serving, it’s been estimated at over 200 milligrams (compared to about 100-150 for a typical 8-ounce cup of coffee). Consuming large quantities of caffeine in energy drinks can have serious health consequences, especially in children and teens, including caffeine toxicity, stroke, anxiety, arrhythmia, and in some cases even death.

Are You Hooked on Soda and Energy Drinks to Give You a Boost?

There are a number of reasons why people drink soda, but many do so because they’re addicted to the ephemeral energy boost they get from the caffeine and sugar. There are, however, natural ways to give your body lasting energy without any of the downsides of consuming fructose, excessive caffeine or artificial sweeteners.
These include:

Eating a healthy diet with limited sugar, fructose and processed foods. See my nutrition plan for a naturally energy-enhancing diet.
Increasing your intake of animal-sourced omega-3 fatty acids, e.g. krill, wild salmon, free-range eggs, to support your energy levels
Release draining emotional stress and negativity with the Emotional Freedom Technique (EFT); this (and Turbo Tapping) can also help you to beat soda cravings
Sleep when you’re tired, and make sure you’re getting high-quality sleep while you’re at it
Exercise, and be sure to include high-intensity interval exercises like Peak Fitness for near endless energy
If you need a supplement, do the above steps first and then try ones that are designed to increase your level of foundational energy at the mitochondrial level. Some of the best are vitamin B12, Ubiquinol and magnesium.

New Revelations Support Diet and Exercise to Reverse Leptin Resistance, Thereby Promoting a Healthy Weight

By Dr. Mercola

Leptin, a hormone that plays a key role in regulating energy intake and energy expenditure, may be one of the most important hormones in your body that will determine your health and lifespan. Insulin is another, and the two work in tandem.
Both insulin and leptin resistance are associated with obesity, and impairment of their ability to transfer the information to receptors is the true foundational core of most all chronic degenerative diseases.
Metabolism can roughly be defined as the chemistry that turns food into life, and therefore insulin and leptin are both critical to health and disease. Insulin and leptin work together to control the quality of your metabolism, and, to a significant extent, your rate of metabolism.
By acquiring a better understanding of how leptin and its receptor interact, researchers now believe they will be able to find new treatments for obesity and other metabolic disorders such as type 2 diabetes, as well as inflammatory diseases like rheumatoid arthritis and psoriasis.
According to recent research published in the journal Molecular Cell,1 the leptin receptor has two hinged legs that swivel until they come in contact with leptin.
Once leptin attaches to the receptor, these legs stop swiveling and become rigid, thereby sending a signal to an enzyme called Janus kinase,2 which has the ability to bind inflammatory cytokines. It is believed that inhibiting the Janus kinases might help improve inflammatory and metabolic disorders.
Alan Saltiel, Director of the Life Sciences Institute, told Medical News Today:3

“This study may help solve an important issue we’ve been struggling with for some time… Since leptin is a master regulator of appetite, understanding why resistance to its effects develops in obesity has been a major obstacle to discovering new drugs for obesity and diabetes. Developing a clear picture of how leptin can bind to its receptor may be the first step in overcoming leptin resistance.”

The fact that the primary focus is on developing drug therapies to “fix” leptin resistance is understandable. That’s the only way the medical industry can make money. However, the way to correct leptin resistance has nothing to do with drugs, and everything to do with diet. But first…

What Exactly is Leptin?

Leptin is a very powerful and influential hormone produced by your fat cells. Your fat, by way of leptin, tells your brain whether you should be hungry, eat and make more fat, whether you should reproduce, or (partly by controlling insulin) whether to engage in maintenance and repair. In short, leptin is the way that your fat stores speak to your brain to let your brain know how much energy is available and, very importantly, what to do with it.
Therefore, leptin may be on top of the food chain in metabolic importance and relevance to disease.
If your leptin signaling is working properly, when your fat stores are “full,” this extra fat will cause a surge in your leptin level, which signals your brain to stop feeling hungry, to stop eating, to stop storing fat and to start burning some extra fat off.
Controlling hunger is a major (though not the only) way that leptin controls energy storage. Hunger is a very powerful, ancient, and deep-seated drive that, if stimulated long enough, will make you eat and store more energy. The only way to eat less in the long-term is to not be hungry, and the only way to do this is to control the hormones that regulate hunger, the primary one being leptin.

How Do You Become Leptin Resistant?

You become leptin-resistant by the same general mechanism that you become insulin-resistant – by continuous overexposure to high levels of the hormone. If you eat a diet that is high in sugar (particularly fructose), grains, and processed foods – the same type of diet that will also increase inflammation in your body – as the sugar gets metabolized in your fat cells, the fat releases surges in leptin.
Over time, if your body is exposed to too much leptin, it will become resistant, just as your body can become resistant to insulin.
The only known way to reestablish proper leptin (and insulin) signaling is to prevent those surges, and the only known way to do that is via diet. As such, diet can have a more profound effect on your health than any other known modality of medical treatment.
A strategic whole food diet, as detailed in my free nutrition plan, that emphasizes good fats and avoids blood sugar spikes coupled with targeted supplements will enhance insulin and leptin sensitivity so that your brain can once again hear the feedback signals from these hormones.

Obesity Helps Spur Cancer’s Growth, New Study Suggests

Leptin and insulin resistance is front and center of the issue of obesity, which is now a problem of epic proportions as it increases your risk for a wide variety of other serious diseases. At least 20 different diseases and conditions are directly attributable to being overweight. This societal problem has emerged in just the past four decades, in large part due to sorely misguided dietary guidelines.
One disease related to excess weight is cancer. And according to recent research, being obese promotes the growth of existing tumors regardless of diet, which may help explain why lean cancer patients often have better outcomes than their obese counterparts.
The animal study, published in the Oct. 15 issue of the journal Cancer Research,4 showed that tumors in obese mice grew much faster than in lean mice eating the same diet. According to the authors:

“In this study, we show that obesity facilitates tumor growth in mice irrespective of concurrent diet, suggesting a direct effect of excess white adipose tissue [fat tissue]. When transplanted into mice, adipose stromal cells can serve as perivascular adipocyte progenitors that promote tumor growth, perhaps helping explain the obesity-cancer link.”

The researchers discovered that the presence of cancer triggered adipose stromal cells – “white” fat cells – to migrate into the blood stream. Once these cells come across a tumor, some of them help provide oxygen and nutrients to the tumor, thereby feeding the growth of the cancer.
Lead researcher Mikhail Kolonin told MedicineNet:5

“The fact that these cells are present in tumors is still an emerging concept. We have shown that not only are they present, but they are also functional and affect tumor growth. Identifying the signals that cause these cells to be recruited to tumors and finding ways to block them might provide a new avenue of cancer treatment.”

Reduce Obesity to Quench Tumor Potential

As stated in the featured article, the implications are clear: “reduce obesity before the appearance of tumors and after.” Unfortunately, there was no mention at all about the role of lifestyle in reducing cancer-boosting “white” fat cells… Again, the focus is on developing drug treatments to convert cancer-boosting “white” fat cells to less harmful “brown” fat (a heat-generating type of fat that burns energy instead of storing it).
If you hinge your health and well-being on that, you’re likely going to miss the boat and join the ranks of cancer statistics. Research has shown that certain groups of people tend to have more brown fat than others, and there are direct correlations between the activation of brown fat and metabolic measures of good health. For example:

Slender people have more brown fat than obese people do
Younger people have more brown fat than elderly people, and
People with normal blood sugar levels have more brown fat than those with high blood sugar

So is there a way to convert harmful white fat into health promoting brown fat, without using a drug? Yes, there is. In one mouse study, the animals converted white fat into brown fat simply by exercising. The study, published in the journal Disease Models and Mechanisms6 in May 2012 found that, during exercise, the animals’ muscles released an enzyme called irisin, which triggered the conversion white fat cells to brown. Another study published in Nature,7 also suggests irisin may be a key to explaining the therapeutic benefits of exercise on metabolic disease. The authors write:

“Irisin acts on white adipose cells in culture and in vivo to stimulate UCP1 expression and a broad program of brown-fat-like development. Irisin is induced with exercise in mice and humans, and mildly increased irisin levels in the blood cause an increase in energy expenditure in mice with no changes in movement or food intake. This results in improvements in obesity and glucose homeostasis.”

Summary

So to summarize: Insulin and leptin resistance are core factors in obesity, which in turn is a risk factor for cancer and may boost tumor growth. But the answer lies not in a pill. To reverse insulin and leptin resistance:

Avoid, sugar, fructose, grains, and processed foods
Eat a healthful diet of whole foods, ideally organic, and replace the grain carbs with:

No-to-low sugar and grain carbs
 As much highly quality healthful fat as you want (saturated and monosaturated). Most people need upwards of 50-70 percent fats in their diet for optimal health. Good sources include coconut and coconut oil, avocados, butter, nuts, and animal fats. Also take a high-quality source of animal-based omega-3 fat, such as krill oil

Similarly, while researchers investigate the pharmaceutical avenues to convert white fat cells to brown in an effort to reduce the potential for cancer growth, other research has already shown that this can likely be achieved through exercise.
As I’ve said before, about 80 percent of the health benefits you reap from a healthy lifestyle comes from your diet, and the remaining 20 percent from exercise – but it’s a very important 20 percent, as it acts in tandem with and boosts the benefits derived from a proper diet. For maximum benefits, you’ll want to make sure to include high-intensity interval training, which is at the heart of my Peak Fitness program. To learn more, please see my previous article: The Major Exercise Mistake I Made for Over 30 Years.

Choline In Eggs And Meat May Influence Gene Expression From Infancy To Adulthood

By Dr. Mercola

Folic acid is perhaps the most well known B vitamin, and is especially important for pregnant women to avoid certain birth defects.
Now researchers have highlighted the importance of another member of the B vitamin complex – choline – which they say may one day be recommended for all pregnant women, the way folic acid is today.

What is Choline?

Choline is an essential nutrient your body makes in small amounts, however you must consume it through your diet to get enough. In adults, choline helps keep your cell membranes functioning properly, plays a role in nerve communications, prevents the buildup of homocysteine in your blood (elevated levels are linked to heart disease) and reduces chronic inflammation.
In pregnant women, choline plays an equally, if not more, important role, helping to prevent certain birth defects, such as spina bifida, and playing a role in brain development.
Prior research has concluded that choline intake during pregnancy “super-charged” the brain activity of animals in utero, indicating that it may boost cognitive function, improve learning and memory, and even diminish age-related memory decline and the brain’s vulnerability to toxins during childhood, as well as conferring protection later in life.1
It’s recommended that pregnant women consume 450 milligrams of choline a day, but the new study found this may not be enough…

Double the Recommended Amount of Choline During Pregnancy Protects Baby from Stress, Metabolic Disorders and More

The new research, published in The FASEB Journal,2 found the consumption of 930 mg of choline in the third trimester of pregnancy was linked to a 33 percent lower concentration of the stress hormone cortisol, compared to those who consumed 430 mg a day.
It’s known that babies exposed to high levels of cortisol in utero, such as might occur if a woman is under extreme stress, facing anxiety or suffering from depression, have an increased risk of stress-related and metabolic disorders. The researchers believe the beneficial impact of choline on lowering cortisol may protect the baby later in life from mental health conditions, high blood pressure and type 2 diabetes.
Interestingly, the higher choline intake led to changes in epigenetic markers in the fetus. Specifically, it affected markers that regulate the hypothalamic-pituitary-adrenal (HPA) axis, which controls hormone production and activity. The higher intake of choline contributed to a more stable HPA axis, which in turn meant lower cortisol levels in the fetus. The changes in fetal genetic expression will likely continue into adulthood, where they play a role in disease prevention.

Epigenetic Changes May Last for Generations

One of the most intriguing aspects of epigenetics is that these changes are often passed down through generations. This was first shown by the research of Francis M. Pottenger, Jr., M.D., who conducted studies on cats in the 1930s. He found that cats fed a healthy, raw-food diet thrived, while those fed on a primarily cooked-meat diet developed degenerative diseases – and those changes continued on through three generations.
Each generation of “junk-food” cats got progressively sicker, until they could no longer reproduce and eventually died off completely by the fourth generation.
Just this year, a study on rats showed those exposed to chemicals or foods that raise estrogen levels during pregnancy produce daughters that have a higher than normal risk for breast cancer – and that risk is passed on to the next two generations.3 It was not genetic mutations that were passed on, but rather epigenetic alterations that modulate the expression of your genes, similar to what was found in the FASEB Journal study.

You Have the Ability to Change Inherited Epigenetic Alterations

The good news about all of this is that even if you inherited a certain increased disease risk from your mother or grandmother (or you think you passed one on to your child), it is not set in stone. As you age, your genome does not change but your epigenome changes dramatically, especially during critical periods of life, such as adolescence. It is influenced by physical and emotional stresses, and lifestyle factors, which, depending on their effects, may either optimize your genetic expression for health or make it favor disease development.
There are literally new epigenetic discoveries being made every day, and it’s becoming quite clear that eating healthy foods is one of the most powerful steps you can take to optimize your genetic expression.
Certain foods, such as broccoli and other cruciferous vegetables, garlic, and onions contain substances that activate tumor suppressor genes and deactivate cancer-associated genes (oncogenes). And now we see that choline appears to influence cortisol production in utero. Your best bet is to take advantage of the many epigenetic influencers in your diet by eating a wide variety of whole foods…
For additional tips, I suggest you read through my comprehensive and recently revised nutrition plan, which will give tools for eating healthy, dealing with stress, and living a lifestyle that will support your epigenetic health.

What are the Best Dietary Sources of Choline?

If you’re currently pregnant, it seems prudent to make sure your diet contains plenty of choline-rich foods, as this will be your primary source of this essential nutrient (most prenatal vitamins do not contain choline). Unfortunately for many vegetarians, animal foods like eggs and meat are some of the best sources of choline, so if you’re a vegan or vegetarian who does not consume any animal foods, you may be at risk of deficiency.
The following chart shows some of the best choline sources to help you choose your foods wisely:4

Food
Serving
Total Choline (mg)

Beef liver, pan fried
3 ounces
355

Wheat germ, toasted
1 cup
172

Egg
1 large
126

Beef, trim cut, cooked
3 ounces
67

Brussel sprouts, cooked
1 cup
63

Broccoli, cooked
1 cup, chopped
62

Salmon
3 ounces
56

Milk, skim
8 fl oz.
38

Peanut butter, smooth
2 tablespoons
20

Are You Concerned Over Genetically Modified Vaccines?

By Dr. Mercola

If you’ve ever had qualms about eating genetically modified (GM) foods, you’d likely be deeply concerned about receiving a GM vaccine as well.
Such vaccines are already being produced – some are even on the U.S. Centers for Disease Control and Prevention’s (CDC) recommended vaccine schedule – even though, as is the case with GM foods, we know very little about their long-term effects.
In the interview above, Vicky Debold, PhD, RN, director of research and patient safety with the National Vaccine Information Center (NVIC), spoke with me about the many reasons to be very wary of this new technology, which is far more intertwined with other biotech “innovations,” like GM food, than you might think.

Nobody Knows What Happens When You Inject People with GM Vaccines

There have been some fair warnings, though. In 2006, researchers wrote in the Journal of Toxicology and Environmental Health:1

“Genetically modified (GM) viruses and genetically engineered virus-vector vaccines possess significant unpredictability and a number of inherent harmful potential hazards… Horizontal transfer of genes… is well established. New hybrid virus progenies resulting from genetic recombination between genetically engineered vaccine viruses and their naturally occurring relatives may possess totally unpredictable characteristics with regard to host preferences and disease-causing potentials.
…There is inadequate knowledge to define either the probability of unintended events or the consequences of genetic modifications.”

Though this was six years ago, little has changed even as the technology has advanced. Today we have several different types of GM vaccines in production, development or research phases, such as:

DNA vaccines: DNA for a microbe’s antigens are introduced into the body, with the expectation that your cells will take up that DNA, which then instructs your cells to make antigen molecules. As the National Institute of Allergy and Infectious Disease (a division of the National Institutes of Health) put it, “In other words, the body’s own cells become vaccine-making factories.”2
Naked DNA vaccines: A type of DNA vaccine in which microscopic particles coated with DNA are administered directly into your cells.
Recombinant Vector vaccines: Similar to DNA vaccines, but they use a virus or bacteria to act as a vector (or “carrier) to introduce microbial DNA into your cells.

There are experimental GM vaccines being developed that use tumorigenic cancer cells and cells from humans, dogs, monkeys, cows, pigs, rodents, birds and insects. What happens when foreign DNA is inserted into the human body is a mystery. Will it trigger undesirable changes in human cells or tissues? Will it combine or exchange genetic material with human DNA? Will it transfer to future generations? No one knows…

“We don’t know what portion of the [GM] DNA can be incorporated into our own genome, we don’t know what portion could be inheritable to our children, we also don’t know what happens when the immune system is exposed to DNA that has been recombined in lots of ways that the human body, through the course of time, has never had any exposure to… what diseases of the immune system may occur because of these exposures,” Debold said.
“Use of foreign DNA in various forms has the potential to cause a great deal of trouble, not only because there is the potential for it to recombine with our own DNA, there is the potential for it to turn the DNA ‘switches,’ the epigenetic parts of the DNA, on and off.”

Vaccine Adjuvants Used in GM Vaccines May be Even More Toxic Than Usual

An adjuvant is added to a vaccine in order to boost the body’s immune reaction to the viral or bacterial antigen contained in a vaccine. Under ideal circumstances, the antigen is what your body responds to and makes antibodies against (e.g. the lab altered viral or bacterial organisms being injected). By boosting your body’s immune response in this artificial way, the vaccine manufacturer can use a smaller amount of antigen, which makes production less expensive and the product more profitable (although definitely not safer, as adjuvants are usually foreign substances, metals or chemicals which can cause the immune system to overreact and attack the host body.)
Aluminum is a common vaccine adjuvant and also a well-known neurotoxin that can cause chronic inflammation in the body, including the brain. Although aluminum adjuvants have been added to inactivated vaccines used for decades in the U.S., aluminum-based adjuvants are not strong enough for GM vaccines, according to Debold, so drug companies are primarily interested in using oil-based adjuvants, like squalene, and other substances that can hyper-stimulate the body’s immune response.
While oil-based vaccine adjuvants like squalene have been proven to generate powerful acute inflammatory immune responses that stimulate increased production of antibodies, they have also been associated with unresolved, chronic inflammation in the body that can cause brain and immune system dysfunction, including autoimmune diseases.3 While the U.S. Food and Drug Administration (FDA) has so far not licensed any vaccines distributed in the U.S. that contain squalene as an adjuvant, squalene adjuvants are used in some vaccines sold in Europe and other countries.

GM Vaccines You May Have Given to Your Kids…

Many are unaware that, despite the completely unknown long-term health consequences, GM vaccines are already in use and have been administered to American infants, children and adults for many years. Among them:

Hepatitis B vaccine: An inactivated recombinant DNA vaccine licensed for newborn infants and children in 1991, in which parts of the hepatitis B virus gene are cloned into yeast
Rotavirus vaccine: Live attenuated vaccines first licensed for infants and children licensed in 2006, which either contain genetically engineered human rotavirus strains or human-bovine hybridized reassortment rotavirus strains4
HPV vaccine (Gardasil or Cervarix): A recombinant vaccine licensed in 2006, which is prepared from virus-like particles (VLP’s) and may also include use of an insect-cell Baculovirus expression vector system for production

Then there are those “hybrid” vaccines that cross the (very narrow) threshold into the GM food realm… for instance, goats are being genetically engineered to become “pharm animals” that carry vaccines in their milk. If the experiments being conducted by researchers from Texas A&M are successful, they will produce an “edible” malaria vaccine, with the ultimate goal being that children drinking the milk will become vaccinated in the process. If vaccines in your milk sounds a bit to “out there,” it shouldn’t, as there are many connections between the companies that make GM food and those that make GM vaccines.

The Close Ties Between GM Foods and GM Vaccines

The companies that make vaccines and GMOs (genetically modified organisms) are deeply intertwined, only recently spinning off or merging to specialize in one or the other. Most vaccine revenues are earned by five companies that together held nearly 80 percent of the market in 2010:5

Sanofi Pasteur
GlaxoSmithKline
Merck & Co.
Pfizer
Novartis

These companies, which use genetic engineering to produce vaccines, are also primarily responsible for the introduction of genetic engineering into the food supply. For instance:

Genetic engineering giant Syngenta (third in total sales in the commercial agricultural seeds market) is the progeny of parent companies Novartis and AstraZeneca.
In 2001, Bayer CropScience became a leading genetically engineered crop producer with its purchase of Aventis’ agribusiness division.6
In 2004, Aventis merged with and into Sanofi. The new Sanofi-Aventis Group became the world’s 3rd largest pharmaceutical company. Aventis Pasteur, the vaccine division of Sanofi-Aventis Group, changed its name to Sanofi Pasteur. Sanofi Pasteur is the vaccines division of Sanofi Group. It is the largest company in the world devoted entirely to vaccines.
Prior to splitting its genetically engineered crop business from its vaccine business, Aventis was known primarily for the StarLink corn debacle (a type of GM corn grown for use in animal feed that contaminated the U.S. food supply in 2000). Bayer now sells Aventis’s Liberty Link crops, engineered to tolerate high doses of the company’s toxic herbicide called Liberty (glufosinate).7
Stauffer Seeds was a spin-off of Stauffer Chemical, formerly a division of Novartis.8 Stauffer Seeds and Prodigene conducted clinical trials on pigs using an edible vaccine for transmissible gastroenteritis virus (TGEV) expressed in corn.9
Prodigene was caught contaminating the food supply with its edible vaccine and the company went out of business, but not before it received a $6-million investment from the Governors Biotechnology Partnership, chaired by Iowa Governor Tom Vilsack. Vilsack, now the Obama Administration’s USDA Secretary, didn’t want any restrictions placed on experimental pharma crops. In reaction to suggestions that pharma crops should be kept away from food crops, Vilsack argued that ‘we should not overreact and hamstring this industry.’10
Prior to 1997, Monsanto (the world leader in GM crops) operated under three parts, the Ag Business (for agricultural products), the Chemicals Business, and the Pharmaceuticals Business, which is now Pharmacia, a subsidiary of Pfizer, the biggest pharmaceutical company in the world and the largest manufacturer of vaccines for food animals.11, 12
GlaxoSmithKline, while producing few products for food or agriculture, has been genetically engineering plants, animals and microorganisms for use in vaccines, pharmaceuticals and medical research.13

Bill Gates, Warren Buffet Supporting Propagation of Both Vaccines and GMOs

The most influential, and, of course, richest advocates for genetic engineering and vaccines are Bill Gates and Warren Buffet. They have business as well as philanthropic interests in these technologies and their Gates Foundation (Buffet has donated over $1.5 billion to the Foundation) allows them to mix business with philanthropy.
They – and the corporations they invite to join them – use the tax shelter of a non-profit organization to invest in for-profit enterprises. Gates & Buffet get tax write-offs for putting money in their foundation, but their foundation can give money (both as grants & investments) directly to for-profit corporations creating for-profit products.
This, obviously, creates huge conflict of interests.
For instance, Monsanto and other biotech companies have collaborated with the Gates Foundation via the Alliance for a Green Revolution in Africa (AGRA) to promote the use of genetically modified (GM) crops in Africa. The Gates Foundation has donated hundreds of millions of dollars to AGRA, and in 2006 Robert Horsch was hired for the AGRA project. Horsch was a Monsanto executive for 25 years. In a nutshell, the project may be sold under the banner of altruism and ‘sustainability,’ but in reality it’s anything but. It’s just a multi-billion dollar enterprise to transform Africa into a GM-crop-friendly continent. The Foundation has also invested heavily in Monsanto stock, purchasing over $23 million worth in 2010.14
The Gates Foundation is also closely partnered with Big Pharma, to whom Bill Gates pledged $10 billion to distribute and administer multiple vaccines to children around the world. This, too, is billed as a humanitarian effort to save lives, but what children living in poverty in developing countries need most is healthy, plentiful food, clean water, better sanitation and improved living conditions. These are the keys to preventing the spread of infectious disease, and they appear to be wholly ignored by Bill Gates, Warren Buffet and non-profit organizations with financial ties to Big Pharma – at the children’s expense.
The Gates Foundation is even funding surveillance of anti-vaccine groups, and the following vaccine companies are supported by the Foundation through both investments and philanthropic projects:

Sanofi
GlaxoSmithKline
Merck
Pfizer
Novartis

Important Movements on the Horizon for Both GM Foods and Vaccines

It’s important to get all the facts before making your decision about vaccination; and to understand that in many state public health laws you still have the legal right to opt out of using a vaccine that you or your child do not want to receive. At present, all 50 states allow a medical exemption to vaccination (medical exemptions must be approved by an M.D. or D.O.); 48 states allow a religious exemption to vaccination; and 17 states allow a personal, philosophical or conscientious belief exemption to vaccination.
However, Washington state now requires parents to obtain the signature of a medical doctor or state-designated medical worker to obtain a philosophical exemption to vaccination. That is because non-medical vaccine exemptions have been restricted in Washington and Vermont and are under attack in California and New Jersey, while there is evidence that medical trade association lobbyists will be working to eliminate or severely restrict vaccine exemptions in Arizona, Connecticut, New York, Colorado and many other states.
Health liberty in America is being threatened by forced vaccination proponents employed by federal and state health departments, who are working with pharmaceutical companies and with Pharma-funded non-profit organizations to encourage government-enforced implementation of “no exceptions” one-size-fits-all vaccine laws. If you want to protect YOUR freedom to make informed, voluntary vaccination decisions in America, you need to take action today. (National vaccination policies are made at the federal level but vaccine laws are made at the state level, and it is at the state level where your action to protect your vaccine choice rights will have the greatest impact).
Signing up to be a user of NVIC’s free online Advocacy Portal at www.NVICAdvocacy.org gives you access to practical, useful information to help you communicate with your elected state legislators and become an effective vaccine choice advocate in your own community. You will get real-time Action Alerts about what you can do if there are threats to vaccine exemptions in your state. With the click of a mouse or one touch on a Smartphone screen, you will be put in contact with YOUR elected representatives so you can let them know how you feel and what you want them to do. Plus, when national vaccine issues come up, you will have all the information you need to make sure your voice is heard.
I also recommend that you join NVIC on facebook, and if you can contribute monetarily, doing so at NVIC.org.
As for GM foods, you can help to pass the United States’ first GMO labeling law – Proposition 37 – that will require labeling of genetically modified (GM) foods and food ingredients – and ban the routine industry practice of labeling and marketing such foods as “natural.” Prop 37 is the best chance we have of defeating the corporate agri-giants, and of forcing food manufacturers to stop hiding dangerous ingredients in our food, without our knowledge.

BPA and Narrowed Arteries: New Study Links Plastics Chemical with Coronary Artery Stenosis

By Dr. Mercola

A new study indicates bisphenol-A (BPA) – a chemical already found to be an endocrine disrupter linked to cancer and reproductive and fetal development problems – may be contributing to narrowed arteries.
Unfortunately, unequivocal proof of the chemical’s dangers to the arteries will be difficult to obtain because experiments on humans are not feasible, but the study’s authors said the growing body of evidence is impressive enough to add BPA exposure to the known risk factors for heart disease.

BPA Linked to Narrowed Arteries

Coronary, carotid and aorticartery stenosis – specific examples of a condition generally known as narrowed arteries – can block blood flow in your arteries, with serious if not lethal health consequences. The narrower your arteries become, the more blood flow gets blocked, which can ultimately lead to not only symptoms of chest pain and tightness but also heart attack and stroke.
In the latest study, researchers looked at levels of urinary BPA levels and artery narrowing in close to 600 people, and found that those with higher urinary BPA levels were more likely to have an increased risk for severe narrowing of the arteries.1 The same research team has conducted three other studies that have also shown an association between BPA and heart risks, including:

A 2008 study that found higher BPA concentrations were associated with heart2
A 2010 study that found higher BPA exposure was consistently associated with heart disease in the general U.S. adult population;3 in fact, U.S. adults with the highest levels of BPA in their urine were more than twice as likely to develop coronary heart disease than those with the lowest levels
A 2012 study that found for each 4.56 ng/mL increase in BPA concentration, there was a 13 percent greater risk of heart disease4

BPA is Found in Nearly Everyone… and Heart Disease is the Leading Cause of Death in the U.S.

While these studies are not proof that BPA causes heart disease, they certainly raise serious questions about why the chemical is still being so widely used across the globe.
BPA is so pervasive that scientists have found that 95 percent of people tested have potentially dangerous levels of BPA in their bodies… and heart disease continues to be the leading cause of death in the United States. BPA is clearly not the only factor involved in heart disease, but given its widespread use – and the fact that it is even commonly found in the umbilical cords of babies in utero – any negative impact it makes on human health could prove disastrous.
Not to mention, heart disease is not the only problem with BPA.
BPA is an endocrine disrupter, which means it mimics and/or interferes with your body’s hormones, subsequently “disrupting” your endocrine system. The glands of your endocrine system and the hormones they release are instrumental in regulating mood, growth and development, tissue function, metabolism, as well as sexual function and reproductive processes.
Some of the greatest concern regarding BPA surrounds early-life, in utero exposure to BPA, which can lead to chromosomal errors in your developing fetus, causing spontaneous miscarriages and genetic damage.
But evidence is also very strong indicating these chemicals are influencing adults and children alike, and leading to decreased sperm quality, early puberty, premature mammary gland development, disrupted reproductive cycles and ovarian dysfunction, cancer and heart disease, among numerous other health problems. Research has even found that “higher BPA exposure is associated with general and central obesity in the general adult population of the United States,”5 while another study found that BPA is associated not only with generalized and abdominal obesity, but also with insulin resistance, which is an underlying factor in many chronic diseases.6

FDA Not Convinced of BPA’s Dangers

Despite the concerning research pouring in, the U.S. Food and Drug Administration (FDA) states that they are aware studies have found BPA is a hazard to people, but says they have “carefully assessed these studies and finds no convincing evidence to support that belief.”7
Unfortunately, although the National Resources Defense Council (NRDC) filed a petition with the FDA calling for the agency to prohibit the use of BPA in products manufactured in the United States, earlier this year the FDA announced that it would be denying NRDC’s petition, noting that it would “make any necessary changes to BPA’s status based on the science.”
In September 2010, Canada declared BPA a toxic substance, but to date no other country has followed suit, although BPA has been banned in baby bottles in Canada, Europe and the United States. Many U.S. companies have voluntarily removed the chemical from their products in response to consumer demand, but it is still widely used. Thanks to the FDA’s refusal to ban BPA from U.S. food packaging, the chemical will continue to experience steady growth in 2012, with an estimated 4.7 million tons set for production this year.
This, in turn, will earn BPA manufacturers a handsome profit of $8 billion.8

Plastics to Canned Goods: How are You Being Exposed to BPA?

You’re probably aware that BPA is often found in plastic food containers and bottles, but plastic is not the only route of exposure. Canned goods, which often have a lining that contains BPA, may in fact be an even greater contributor. In one study, eating canned soup for five days increased study participants’ urinary concentrations of BPA by more than 1,000% compared to eating freshly made soup.9
The researchers believe canned goods may be an even greater source of exposure to BPA than plastics. So watch out for canned tomatoes and other canned vegetables, canned soups and canned beverages, like soda or juice.
Other often-overlooked routes of exposure include:

Receipts: A study in Analytical and Bioanalytical Chemistry found that of 13 thermal printing papers (the type often used for receipts) analyzed, 11 contained BPA.10 Holding the paper for just 5 seconds was enough to transfer BPA onto a person’s skin, and the amount of BPA transferred increased by about 10 times if the fingers were wet or greasy.
Currency: In a study published in Environmental Science and Technology, researchers analyzed paper currencies from 21 countries for the presence of BPA, and the chemical was detected in every sample.11 They also measured the transfer of BPA from thermal receipt paper to currency by placing the two together in a wallet for 24 hours. This dramatically increased the concentrations of BPA on the money, which again suggests that receipts are highly contaminated.

So in order to really reduce your BPA exposure, you need to watch out for:

Canned foods and soda cans
All BPA-containing plastics and food packaging
Certain tooth sealants
Certain BPA-free plastics (which can contain similar endocrine-disrupting chemicals)
Receipts and currency (seek to limit or avoid carrying receipts in your wallet or purse, as it appears the chemical is transferring onto other surfaces it touches. It would also be wise to wash your hands after handling receipts and currency, and avoid handling them particularly if you’ve just put on lotion or have any other greasy substance on your hands, as this may increase your exposure)

Why Did the FDA Approve a Generic Version of this Dangerous Drug?

By Dr. Mercola

Actos – the brand name for a drug used to treat type 2 diabetes – is presently embroiled in thousands of lawsuits alleging that the drug causes severe side effects including heart failure, macular edema and bladder cancer.
Even so, the U.S. Food and Drug Administration (FDA) has gone ahead and approved Mylan Lab’s plan to sell a generic version of this dangerous drug (pioglitazone), justifying their reasoning by saying this gives patients “affordable treatment options.”
The FDA addressed the heart failure and bladder cancer possibilities with a recommendation that doctors carefully monitor patients taking the new generic version… however, what the new generic drug really does is expose even more people to this drug class’ unacceptable, and sometimes deadly, side effects – to treat a disease that responds very well to dietary and exercise changes!

Actos and its Generic Riddled With Serious Health Risks

Actos works by helping to control blood sugar levels in people with type 2 diabetes, a method that “experts” say will help to reduce the long-term health complications of diabetes and keep the disease under control. 
But diabetes treatments concentrating merely on lowering blood sugar can actually worsen, rather than remedy, the underlying metabolic dysfunction that is at the root of type 2 diabetes. And along with completely ignoring the underlying reasons why the diabetes developed in the first place, Actos carries some very serious health risks.
For starters, Actos has a Boxed Warning that states the drug may cause or worsen heart failure.
This risk has been somewhat overshadowed by the attention given to Avandia, a similar diabetes drug in the same class that has been found to cause a 43 percent increased risk of heart attack, and a 64 percent higher risk of cardiovascular death, compared to patients treated with other methods.1 However, although Actos is regarded as a “safer” option for your heart than Avandia, it also poses serious risks to your heart.
And that’s not all.
Actos’ label also notes that the use of pioglitazone for more than one year may be associated with an increased risk of bladder cancer. In fact, new research just out from the Perelman School of Medicine at the University of Pennsylvania shows that people who take this drug for five years or more are two to three times more likely to develop bladder cancer than those who take a different form of diabetes drug.2 
Actos has already been removed from the market in both Germany and France due to the bladder cancer risks… but in the United States we now have not only Actos, but a generic version as well!
In a twist to the story, two days before the FDA approved Mylan’s generic Actos, Watson Pharmaceuticals sued the FDA for not following through on giving Watson exclusivity for its generic version of Actos, which was originally scheduled to be released on August 17.
There are as many as 13,000 Actos lawsuits currently pending, related to both heart failure and bladder cancer cases, as well as other side effects including bone fractures and lactic acidosis.

Actos Whistleblower Reveals Fraud, Deception and Serious Dangers

Dr. Helen Ge worked for Takeda (Actos’ maker) in the company’s pharmacovigilance division. There, Dr. Ge was in charge of reviewing side effects of Actos that were reported by patients and doctors. She then prepared safety reports that were filed with the FDA – reports that Ge says she was ordered to water-down or not report at all, so Actos would look safer than it actually was.
She believes Actos is even more dangerous than Avandia, the diabetes drug mentioned earlier that has been removed from pharmacies because of the risk of heart attacks. Dr. Ge says that besides bladder cancer and tumors Actos is also connected to heart attacks and stroke, suicide, schizophrenia, homicidal ideation, and renal failure.

Dr. Ge filed her lawsuit in September 2011, alleging that Takeda, like many pharmaceutical companies, was interested in protecting their profits, first and foremost, which makes the approval of a generic version of this drug all the more unsettling. Actos is Takeda’s most profitable drug, bringing in $3.4 billion in annual sales.
Dr. Ge noted:3

“Takeda’s motivation to fraudulently report and under-report the serious adverse events was driven by an economic desire to falsely enhance Actos’s safety profile and to increase sales.”

So far Avandia has been the poster child for what is wrong with drug treatment of type 2 diabetes. And it took nearly 10 years of the drug being on the market for the FDA to take action and restrict access to this dangerous drug. In the meantime, millions of people have taken Avandia and have been exposed to these unacceptably high-risk side effects, for a drug that in no way treats the underlying causes of diabetes.
More than 80,000 diabetics have suffered from strokes, heart failure or other complications including lethal heart attacks from this dangerous drug… and now it appears Actos and its generic versions may be stepping in to fill its shoes.

What You Should Know About Diabetes Drugs…

Drugs can’t cure diabetes, as they do nothing to address the underlying causes. Drugs like Actos and Avandia work by tricking diabetes patients’ bodies to become more sensitive to their own insulin, helping to control blood sugar levels. Tricking the body in non-ancestral and time-honored ways in which our biochemistry and genetics have adjusted to for many eons typically results in devastating effects eventually if pursued long enough, and the Actos and Avandia experience confirms this.
But it is important to understand that diabetes is NOT strictly a blood sugar disease like your doctor may have led you to believe. Type 2 diabetes is actually a disease caused by insulin resistance and faulty leptin (a relatively recently discovered hormone produced by fat) signaling, both of which are regulated through your diet.
Conventional treatment, which is focused on suppressing the symptom of elevated blood sugar rather than addressing the underlying causes, is doomed to fail in most cases.
Because type 2 diabetes arises from faulty leptin and insulin signaling it is therefore a fully preventable condition that can be controlled or reversed by recovering your insulin and leptin sensitivities. However, the only known long-term effective way to reestablish proper leptin and insulin signaling is through proper diet and exercise. There is NO drug that can safely accomplish this – a fact that makes the current disease paradigm even more tragic, as diabetes continues to skyrocket, and the conventional treatments are needlessly killing diabetics prematurely.
If you have type 2 diabetes, I strongly suggest that you consult with a health care practitioner who is knowledgeable about its true underlying cause, and who can work with you to reverse the condition without the use of drugs. Some of the most helpful guidelines to successfully do this include:

Severely limit or eliminate sugar and grains in your diet, especially fructose, which is far more detrimental than any other type of sugar. Following my Nutrition Plan will help you do this without too much fuss.
Exercise regularly. Exercise is an absolutely essential factor, and without it, you’re unlikely to get this devastating disease under control. It is one of the fastest and most powerful ways to lower your insulin and leptin resistance. I recommend including some high-intensity Peak Fitness exercises for optimal results.
Avoid synthetic trans fats.
Get plenty of omega-3 fats from a high quality, animal-based source, such as krill oil.
Optimize your vitamin D levels. Recent studies have revealed that getting enough vitamin D can also have a powerful effect on normalizing your blood pressure, which has virtually identical response improvement to diabetic interventions.
Optimize your gut flora. Your gut is a living ecosystem, full of many different types of bacteria. The more beneficial bacteria you have, the more likely your blood sugar will be in balance. Indeed, new research published in the journal Lipids in Health and Disease found that a combination of prebiotics and probiotics, taken for 30 days, resulted in a significant reduction in fasting blood sugar in human subjects.4

Fortunately, optimizing your gut flora is relatively easy. You can reseed your body with good bacteria by eating fermented foods (like natto, kefir, raw organic cheese, miso, and fermented vegetables) or by taking a high-quality probiotic supplement.

Address any underlying emotional issues and/or stress. Non-invasive tools like the Emotional Freedom Technique (EFT) can be extremely helpful and effective.
Get enough high-quality sleep every night.
Monitor your fasting insulin level. This is every bit as important as your fasting blood sugar. You’ll want your fasting insulin level to be between 2 and 4. The higher your level, the worse your insulin sensitivity is.

Anemia Drug Made Billions but at What Cost?

By Dr. Mercola

Three anemia drugs – Epogen, Procrit and Aranesp – have been among the best-selling prescription drugs in the United States for years, generating more than $8 billion a year for their makers, Amgen and Johnson & Johnson.
They were blockbuster drugs that stimulate your body to produce new red blood cells, which supposedly helped boost kidney and cancer patients’ energy and, ultimately, enhanced their lives.
But now, after millions of people have taken these drugs, it’s come out that the benefits were “wildly overstated, and potentially lethal side effects, such as cancer and strokes, were overlooked.”1
Worse still, the Washington Post has uncovered a series of unsettling events that show just how far drug makers were willing to go to get rich…

Doctors Earned Profits of Up to 30 Percent Just for Prescribing the Drugs

And this was one of the first problems. Drug makers lobbied Congress in order to put a system into place so that doctors and hospitals would be reimbursed more for the drugs they prescribed to Medicare patients than what they actually paid for them. The markup could be as high as 30 percent, and the higher the dose prescribed, the more money they made.
According to Charles Bennett, endowed chair at the Medication Safety and Efficacy Center of Economic Excellence at the University of South Carolina, in the Washington Post:

“It was just so easy to do – you put this stuff in the patient’s arm, and you made thousands of dollars… An oncologist could make anywhere from $100,000 to $300,000 a year from this alone. And all the while they were told that it was good for the patient.”

Higher Doses Pushed to a Growing Number of Patients

Initially, patients with kidney disease, who often suffer from anemia, were the key target market for the drugs. If anemia is severe enough, blood transfusions are required to boost red blood cell counts. Epogen, Procrit, and, later, Aranesp, were able to accomplish the same boost in blood cells without the need for transfusions.
The Washington Post reported:

“The trouble would arise as the drugmakers won FDA approval for vastly expanded uses, pushing it in larger doses, for milder anemia and for patients with a wider array of illnesses. Very quickly, the market included nearly all dialysis patients, not just the roughly 16 percent who required blood transfusions. The size of average doses would more than triple. And over the next five years, the FDA would approve it to treat anemia in patients with cancer and AIDS, as well as those getting hip and knee surgery.

The key to their marketing was the claim that the drugs at higher doses could make patients feel better. By 1994, the drug’s label, approved by the FDA, advertised a range of benefits: ‘statistically significant improvements for… health, sex life, well-being, psychological effect, life satisfaction, and happiness.'”

These claims, however, were based on a series of incomplete and never-published research, some of which were drawn out over a decade or more only to show inconclusive results. One safety study on cancer patients that was supposed to be finished in 2008 is still not complete, and won’t be until 2017, according to Amgen, which will be nearly 25 years after the drugs were approved for cancer patients.
And as it turns out, the claims that the drugs lead to improved quality of life have since been withdrawn because they don’t meet the U.S. Food and Drug Administration’s (FDA) standards of proof.

Higher Doses Increased Patients’ Risk of Dying – Study Results Missing Key Data

In 1998, the Normal Hematocrit Trial was published, which explored giving higher doses of drugs to dialysis patients in order to boost their red blood cell count above those generally achieved with transfusion.2 The study did, in fact, find that patients receiving the higher drug dose were dying or having heart attacks at a higher rate than those receiving the lower dose; the trial was actually halted because of this.
However, rather than sounding an alarm bell, when the study was published the authors downplayed the danger, calling the increased death and heart attack rate “not significant.” And while no difference was found in quality of life between patients receiving the higher or lower dose, this was not noted in the published study. (Four of the study’s eight authors were employed by Amgen, and two have served as consultants.)
As the years went by, health care providers and the drug companies continued to profit from the ever-rising doses of these drugs being prescribed – despite continued studies coming out questioning their safety. It wasn’t until years later, in 2011, that the FDA put out a safety announcement calling for more conservative dosing of the drugs “because of data showing increased risks of cardiovascular events.”3
The Washington Post reported:

“For years, a small Bethesda-based nonprofit think tank, the Medical Technology and Practice Patterns Institute, had been publishing studies that challenged the conventional enthusiasm for the drug and the government policies that it said promoted their overuse.
Then in November 2006, a study published in the New England Journal of Medicine reported that kidney patients targeted for higher doses were linked to higher risks of hospitalization, strokes and death. In December, a group of Danish researchers said that it had stopped a trial of Aranesp in cancer patients because of an increase in deaths and tumor growths. And that was just the beginning of the bad news…”

The FDA Finally Cracks Down

The Danish research seemed to be the breaking point for the anemia drug trio.

“‘Then the FDA cracked down,’ The Washington Post reported. ‘The drugs’ use was ruled out in cancer patients considered curable, it was ruled out in patients considered just slightly anemic, maximum recommended doses were lowered, and the agency told doctors in many cases to use the smallest amount possible to avoid a blood transfusion.

The agency also began to look askance at the alleged benefits, for which the evidence, in retrospect, seemed flimsy. There was no solid proof, under revised FDA guidelines for such measures, that use of the drugs leads to ‘statistically significant’ improvements in happiness and other benefits, the agency said. Those quality-of-life claims, once so critical to the drug’s adoption, were removed from the label.

…Last year, nearly two decades after the Office of the Inspector General first suggested it, the economic incentives to use more of the drugs on patients in dialysis disappeared.”

No major class-action suits have so far been filed against the drugs’ makers; it is often difficult to prove the drugs were the cause of death, particularly because patients who received them were typically already facing chronic health problems. Still, Amgen has put aside a reported $780 million to settle various claims, including some for alleged illegal sales tactics – a paltry compensation to those who have lost loved ones. This is, unfortunately, just the latest drug scandal to be brought to the public’s attention… and it surely won’t be the last.

Pharma Giant Pfizer Fined for Bribing Officials in Eastern Europe and China

Earlier this month, it was revealed that U.S. pharmaceutical giant Pfizer and its subsidiary Wyeth have been charged with paying off officials, doctors and healthcare professionals in Eastern Europe and China to secure approval and registration of the companies’ products.

The company allegedly paid millions of dollars in bribes from 2001 to 2007. The bribery was so blatant and entwined in the sales practices that they even offered points and bonus programs to improperly reward foreign officials who proved to be the best customers, according to the head of the SEC’s Foreign Corrupt Practices Act Unit. Obviously, such corrupt pay-offs puts honest companies at a disadvantage, James McJunkin, assistant director of the Washington field office of the Federal Bureau of Investigation pointed out.4

And that is the over-riding theme we see again and again – these companies are typically NOT honest, yet we trust them with the most sacred possession we have, our health. For punishment, Pfizer will be paying various fines ranging from $15 million to $26 million – barely a slap on the wrist for a company that makes billions of dollars a year.

Big Pharma’s Lack of Ethics, Regard for Patient Safety Seemingly Knows No Bounds

If it seems like the number of lawsuits that Big Pharma is settling – many of them out of court without going to trial – are rising, they are. From Merck’s $950-million Vioxx deal to the latest announcement that Pfizer has made an $896-million settlement with Prempro victims, the deals show no signs of stopping. Most of the lawsuits are being filed in conjunction with, or aided by, the U.S. Department of Justice, many of them originating from former employees-turned-whistleblowers who divulged marketing misdoings by their employers.

The litigation and settlements are starting to rattle the drug industry, which is becoming no stranger to billion-dollar settlements. Most likely near the end of 2012, Johnson & Johnson reportedly will settle for as much $2.2 billion for its fraudulent marketing of the antipsychotic drug Risperdal.

That amount rivals what was the largest health care fraud settlement to date – $2.3 billion paid by Pfizer in 2009, also for illegally promoting uses of four of its drugs. However, now it’s come out that GlaxoSmithKline has agreed to a whopping $3-billion settlement – the largest in U.S. history for health care fraud – with the U.S. government, again for advertising drugs for unapproved uses, along with using gifts to persuade doctors to prescribe the drugs.5

Unfortunately, Americans are disproportionally supporting this behemoth of an industry. Americans, including children, are the most drugged people in the entire world, with the average adult taking 11 prescription drugs – each of which comes with an average of 70 different potential side effects that are then typically addressed with even more drugs…

The situation has gotten out of hand, especially since there’s a mountain of evidence supporting the use of alternatives, and there’s very strong evidence that some “alternative” treatments, such as diet and exercise, are FAR more effective, not to mention safer, than any of the drugs currently in use. My site is chock full of free comprehensive recommendations that can serve as an excellent starting point to break free from this fatally flawed paradigm. The tools I provide on this site will help you to reduce your reliance on the broken health care system, including its overuse of drugs, and provide you with the tools and resources to Take Control of Your Health.